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Single delivery of an Adeno-Associated viral Construct to Transfer the CASQ2 Gene to Knock-In Mice Affected by Catecholaminergic Polymorphic Ventricular Tachycardia Is Able to Cure the Disease From Birth to Advanced Age
(American Heart Association, 2014-06)
Background — Catecholaminergic polymorphic ventricular tachycardia is an inherited arrhythmogenic disorder characterized by sudden cardiac death in children. Drug therapy is still insufficient to provide full protection ...
Luminal calcium regulates calcium release in triads isolated from frog and rabbit skeletal muscle
(1995)
Triads isolated from frog and rabbit skeletal muscle were equilibrated with different external [Ca2+], ranging from 0.025 to 10 mM. Vesicular calcium increased with external [Ca2+] as the sum of a linear plus a saturable ...
Expression of calcium-buffering proteins in rat intrinsic laryngeal muscles
(Wiley-Blackwell, 2015-06-01)
Intrinsic laryngeal muscles (ILM) are highly specialized muscles involved in phonation and airway protection, with unique properties that allow them to perform extremely rapid contractions and to escape from damage in ...
Cardiac function and intracellular Ca2+ handling proteins are not impaired by high-saturated-fat diet-induced obesity
(Assoc Bras Divulg Cientifica, 2019-01-01)
Obesity is often associated with changes in cardiac function; however, the mechanisms responsible for functional abnormalities have not yet been fully clarified. Considering the lack of information regarding high-saturated-fat ...