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Mostrando ítems 1211-1220 de 2094
Novelty modulates the stimulating motor effects of ethanol in preweanling rats
(Pergamon-Elsevier Science Ltd, 2009-05)
During early ontogeny heterogeneous rats are sensitive to ethanol's stimulating effects. In adulthood locomotor activity in a novel environment is a valuable predictor of acute sensitivity to the activating effects of ...
Allosterically linked noncompetitive antagonist binding sites in the resting nicotinic acetylcholine receptor ion channel
(Elsevier Science Inc, 2002-07-01)
Previous studies have established the presence of overlapping binding sites for the noncompetitive antagonists (NCAs) amobarbital, tetracaine, and 3-trifluoromethyl-3-(m-[ 125 I]iodophenyl) diazirine ([ 125 I]TID) within ...
The fungal endophyte Fusarium solani provokes differential effects on the fitness of two Lotus species
(Elsevier France-editions Scientifiques Medicales Elsevier, 2019-11)
The interactions established between plants and endophytic fungi span a continuum from beneficial to pathogenic associations. The aim of this work was to isolate potentially beneficial fungal endophytes in the legume Lotus ...
Growth and development of AtMSH7 mutants in Arabidopsis thaliana
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2020-01)
DNA mismatch repair (MMR) is a highly conserved biological pathway that improves the fidelity of DNA replication and recombination. MMR is initiated when MutS proteins recognize mismatches and small loops of unpaired ...
Steric Control of the Rate-Limiting Step of UDP-Galactopyranose Mutase
(American Chemical Society, 2018-07)
Galactose is an abundant monosaccharide found exclusively in mammals as galactopyranose (Galp), the six-membered ring form of this sugar. In contrast, galactose appears in many pathogenic microorganisms as the five-membered ...
Antioxidative activity in the seeds of 28 Vicia species from Southern Spain
(Wiley Blackwell Publishing, Inc, 2011-10)
The antioxidant activity of the polyphenols extracted from the seeds of 28 Vicia species collected in southern Spain was investigated. The seeds were all taken from wild populations, although some of these species are or ...
Comet assay in gill cells of Prochilodus lineatus exposed in vivo to cypermethrin
(Academic Press Inc Elsevier Science, 2013-11)
Agricultural chemicals can induce genetic alterations on aquatic organisms that have been associated with effects on growth, reproduction and population dynamics. The evaluation of DNA damage in fish using the comet assay ...
Serological diagnosis of Toxoplasmosis disease using a fluorescent immunosensor with chitosan-ZnO-nanoparticles
(Academic Press Inc Elsevier Science, 2019-01)
This article describes a microfluidic LIF immunosensor for the quantitative determination of anti-Toxoplasma gondii IgG (anti-T. gondii) specific antibodies. The serological detection of these antibodies plays a crucial ...
Jaburetox, a urease‐derived peptide: Effects on enzymatic pathways of the cockroach Nauphoeta cinerea
(Wiley-liss, div John Wiley & Sons Inc., 2020-08)
Jaburetox is a recombinant peptide derived from one of the Canavalia ensiformis urease isoforms. This peptide induces several toxic effects on insects of different orders, including interference on muscle contractility in ...
Engineering the loop region of a homeodomain-leucine zipper protein promotes efficient binding to a monomeric DNA binding site
(American Chemical Society, 2004-12)
Plant homeodomain-leucine zipper (HD-Zip) proteins, unlike many animal homeodomains (HDs), are unable to bind DNA as monomers. To investigate the molecular basis of their different behavior, we have constructed chimeras ...