Buscar
Mostrando ítems 31-40 de 474
Cytokine-enhanced vaccine and suicide gene therapy as adjuvant treatments of metastatic melanoma in a horse
(British Veterinary Association, 2009-02)
We evaluated the safety, efficacy and anti-tumour effects of a surgery adjuvant treatment on an equine patient with metastatic malignant melanoma. This approach combined suicide gene therapy with a subcutaneous vaccine ...
Development of a universa CTL-based vaccine for influenza
(Wiley, 2013-01)
In pursuit of better influenza vaccines, many strategies are being studied worldwide. An attractive alternative is the generation of a broadly cross-reactive vaccine based on the induction of cytotoxic T-lymphocytes (CTL) ...
CpG DNA as a Th1-promoting adjuvant in immunization against Trypanosoma cruzi
(Elsevier, 2000-09)
Th1-type immune response plays a critical role in resistance to Trypanosoma cruzi infection. We asked whether a synthetic oligodeoxynucleotide that contains immunostimulatory CpG motifs (CpG ODN), known to promote a Th1 ...
Oral delivery of Brucella spp. recombinant protein U-Omp16 abrogates the IgE-mediated milk allergy
(Landes Bioscience, 2014-05)
Food allergies are increasingly common disorders and no therapeutic strategies are yet approved. The unlipidated Omp16 (U-Omp16) is the outer membrane protein of 16 kDa from B. abortus and possesses a mucosal adjuvant ...
Archaeosomes display immunoadjuvant potential for a vaccine against Chagas disease
(Taylor & Francis, 2013-02)
Archaeosomes (ARC), vesicles made from lipids extracted from Archaea, display strong adjuvant properties. In this study, we evaluated the ability of the highly stable ARC formulated from total polar lipids of a new Halorubrum ...
Probiotic bacteria and their cell walls induce Th1-Type immunity against Salmonella Typhimurium Challenge
(Frontiers Media S.A., 2021-05-12)
Probiotics have been associated with a variety of health benefits. They can act as adjuvant to enhance specific immune response. Bacterial cell wall (CW) molecules are key structures that interact with host receptors ...
Hyaluronan degrading silica nanoparticles for skin cancer therapy
(Royal Society of Chemistry, 2013-07)
We report the first nanoformulation of Hyaluronidase (Hyal) and its enhanced adjuvant effect over the free enzyme. Hyaluronic acid (HA) degrading enzyme Hyal was immobilized on 250 nm silica nanoparticles (SiNP) maintaining ...
A plasmid encoding the extracellular domain of CD40 ligand and MontanideTM GEL01 as adjuvants enhance the immunogenicity and the protection induced by a DNA vaccine against BoHV-1
(Elsevier, 2021-02)
DNA vaccines are capable of inducing humoral and cellular immunity, and are important to control bovine herpesvirus 1 (BoHV-1), an agent of the bovine respiratory disease complex. In previous work, a DNA plasmid that encodes ...
FMD empty capsids combined with the immunostant particle adjuvant -ISPA or ISA206 induce protective immunity against foot and mouth disease virus
(Elsevier, 2021-05)
Foot and Mouth Disease Virus (FMDV) causes economy losses and is controlled by vaccination in many countries. Vaccine formulations based on empty capsids or Virus-Like Particles (VLPs) have the advantage of avoiding the ...
Early protection against foot-and-mouth disease virus in cattle using an inactivated vaccine formulated with Montanide ESSAI IMS D 12802 VG PR adjuvant
(Elsevier, 2014-04-17)
Foot and mouth disease is an acute disease of cattle with a broad distribution around the world. Due to the fast spread of FMDV infections, control measures must be applied immediately after an outbreak, such as the use ...