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Comparative assessment of critical quality attributes of sildenafil tablets
(Dissolution Technologies, Inc, 2021-02)
Sildenafil citrate is a selective inhibitor of the enzyme phosphodiesterase type 5, used to treat erectile dysfunction in adults and pulmonary hypertension, mainly in children. This work aimed to perform a comparative study ...
Novel mucoadhesive extended release tablets for treatment of oral candidosis: "In vivo" evaluation of the biopharmaceutical performance
(John Wiley & Sons Inc, 2009-12)
Mucoadhesive tablets containing nystatin (10 mg) were evaluated in vivo. The assays were carried out with 12 healthy volunteers and the concentration of nystatin in saliva was determined at different times. Tablets remained ...
Alternative and improved method for the simultaneous determination of fexofenadine and pseudoephedrine in their combined tablet formulation
(Elsevier Science, 2007-12)
An alternative method for the determination of fexofenadine (FEX) and pseudoephedrine (PSE) in their combined tablet formulation has been developed, employing the partial least squares (PLS) analysis of spectral data of ...
Thermal behaviour and biological activity against Aedes aegypti (Diptera: Culicidae) of permethrin and pyriproxyfen in a smoke-generating formulation
(John Wiley & Sons Ltd, 2009-11)
Background: The most common ways to control dengue vector Aedes aegypti (L.) are larval source reduction in domestic habitats and ground application of small quantities of aerosol insecticide (ultralow volume). Nevertheless, ...
Binder-free twin-screw melt granulation: An effective approach to manufacture high-dose API formulations
(Elsevier Science, 2021-09-05)
This study investigates the use of twin-screw binder-free melt granulation (BFMG) in the development of high- dose solid dose formulations for low melting point thermally stable drugs. Both ibuprofen and guaifenesin are ...
Urinary excretion of ciprofloxacin after administration of extended release tablets in healthy volunteers. Swellable drug-polyelectrolyte matrix versus bilayer tablets
(Springer Verlag, 2018-02)
This paper builds on a previous paper in which new ciprofloxacin extended-release tablets were developed based on a ciprofloxacin-based swellable drug polyelectrolyte matrix (SDPM-CIP). The matrix contains a molecular ...
Effect of silicification on the tableting performance of cellulose II: A novel multifunctional excipient
(Pharmaceutical Society of JapanDiseño y Formulación de Medicamentos Cosméticos y AfinesTokyo, Japón, 2023)
A comparative in vitro assay of drug release performance of pyridostigmine bromide tablets
(Dissolution Technologies, Inc, 2007-11)
Myasthenia gravis is an autoimmune disease that destroys key components of the neuromuscular system. The most common therapy uses reversible inhibitors of cholinesterase activity, such as pyridostigmine bromide (PB). The ...
Formulation development and evaluation of Silybum marianum tablets
(Jardim Botânico do Rio de Janeiro. Instituto de Pesquisas, 2020-07)
En medicina popular, Silybum marianum se usa como agente hepatoprotector. La silimarina es su componente principal. El presente trabajo trata de la formulación y evaluación de tabletas de S. marianum a partir de extracto ...