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Retina stem cells, hopes and obstacles
(Baishideng Publishing, 2021-10-26)
Retinal degeneration is a major contributor to visual dysfunction worldwide. Although it comprises several eye diseases, loss of retinal pigment epithelial (RPE) and photoreceptor cells are the major contributors to their ...
Cyclic recovery of adenovirus in a stem cell transplant recipient: An inverse association with graft-versus-host disease
(Nature Publishing Group, 2003-02)
Adenovirus (AdV) infections have been increasingly recognized as significant pathogens that may cause severe morbidity and mortality among stem cell transplant (SCT) recipients. AdV can cause localized infections such as ...
What are the effects of stem cell transplantation for people with ischemic stroke?
(Wiley, 2019-07)
Low‐certainty evidence suggests that for adults with acute, subacute, or chronic middle cerebral artery territory infarct, receiving stem cell transplantation may have little effect or an unimportant impact on neurologic ...
Stem cell transplantation for children with hemophagocytic lymphohistiocytosis: results from the HLH-2004 study
(American Society of Hematology, 2020-08-11)
We report the largest prospective study thus far on hematopoietic stem cell transplantation (HSCT) in hemophagocytic lymphohistiocytosis (HLH), a life-threatening hyperinflammatory syndrome comprising familial/genetic HLH ...
Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells
(Cell Press, 2020-06)
The availability of an autologous transplantable auxiliary liver would dramatically affect the treatment of liver disease. Assembly and function in vivo of a bioengineered human liver derived from induced pluripotent stem ...
Fluorescence properties of curcumin-loaded nanoparticles for cell tracking
(Dove Press, 2018-12)
Background: Posttransplant cell tracking, via stem cell labeling, is a crucial strategy for monitoring and maximizing benefits of cell-based therapies. The structures and functionalities of polysaccharides, proteins, and ...
Mesenchymal stem cell therapy facilitates donor lung preservation by reducing oxidative damage during ischemia
(Hindawi Publishing Corporation, 2019-08)
Lung transplantation is a lifesaving therapy for people living with severe, life-threatening lung disease. The high mortality rate among patients awaiting transplantation is mainly due to the low percentage of lungs that ...
A new experimental protocol for preferential differentiation of mouse embryonic stem cells into insulin-producing cells
(Cognizant Communication Corp, 2008-12)
Mouse embiyonic stem (ES) cells have the potential to differentiate into insulin-producing cells, but efficient protocols for in vitro differentiation have not been established. Here we have developed a new optimized ...
EGFP transgene: a useful tool to track transplanted bone marrow mononuclear cell contribution to peripheral remyelination
(Springer, 2018-04)
Bone marrow mononuclear cells (BMMC) constitute a heterogeneous population with potential to promote tissue regeneration. For this reason, this cell fraction has recently become a therapeutic alternative to mesenchymal ...
Wound healing treatment by transplantation of umbilical cord mesenchymal stem cell subpopulation
(SAGE Publications, 2021-05)
In normal physiological conditions, restoration of a functional epidermal barrier is highly efficient; nevertheless, when it fails, one of the main consequences is a chronic ulcerative skin defect, one of the most frequently ...