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Local regulation of immune genes in rainbow trout (Oncorhynchus mykiss) naturally infected with Flavobacterium psychrophilum
(Elsevier, 2018)
Flavobacterium psychrophilum is the etiological agent of bacterial cold water disease (BCWD), also referred to as rainbow trout fry syndrome (RTFS), a disease with great economic impact in salmonid aquaculture. Despite ...
Quantification of Leishmania (Viannia) Kinetoplast DNA in Ulcers of Cutaneous Leishmaniasis Reveals Inter-site and Inter-sampling Variability in Parasite Load
(Public Library of Science, 2015)
BACKGROUND: Cutaneous leishmaniasis (CL) is a skin disease caused by the protozoan parasite Leishmania. Few studies have assessed the influence of the sample collection site within the ulcer and the sampling method on the ...
Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile
(Public Library of Science, 2017)
Latin Americans are highly heterogeneous regarding the type of Native American ancestry. Consideration of specific associations with common diseases may lead to substantial advances in unraveling of disease etiology and ...
Polymerase chain reaction detection of leishmania kDNA from the urine of Peruvian patients with cutaneous and mucocutaneous leishmaniasis
(American Society of Tropical Medicine and Hygiene, 2011)
We hypothesized that Leishmania kDNA may be present in urine of patients with cutaneous leishmaniasis (CL). Urine samples and standard diagnostic specimens were collected from patients with skin lesions. kDNA polymerase ...
Nanocarriers for Skin Applications: Where Do We Stand?
(Wiley VCH Verlag, 2021-09)
Skin penetration of active molecules for treatment of diverse diseases is a major field of research owing to the advantages associated with the skin like easy accessibility, reduced systemic-derived side effects, and ...
Can dermal delivery of therapeutics be improved using thermoresponsive nanogels?
(Future Medicine, 2019-11)
Skin, being the largest organ of the body, has attracted a lot of attention in recent years as a vector to deliver awide spectrum of cargo molecules to treat multiple conditions, including genetic disorders, infections by ...
Genetic components of human pain sensitivity: A protocol for a genome-wide association study of experimental pain in healthy volunteers
(BMJ Publishing Group, 2019)
INTRODUCTION: Pain constitutes a major component of the global burden of diseases. Recent studies suggest a strong genetic contribution to pain susceptibility and severity. Whereas most of the available evidence relies on ...
Application of crispr/cas9-based reverse genetics in leishmania braziliensis: Conserved roles for hsp100 and hsp23
(MDPI, 2020)
The protozoan parasite Leishmania (Viannia) braziliensis (L. braziliensis) is the main cause of human tegumentary leishmaniasis in the New World, a disease affecting the skin and/or mucosal tissues. Despite its importance, ...
Three Cases of Canine Dermatomyositis-Like Disease
(Universidade Federal do Rio Grande do Sul, 2018)
Upregulation of PI3K/AKT/mTOR, FABP5 and PPARβ/δ in human psoriasis and imiquimodinduced murine psoriasiform dermatitis model
(Acta Dermato-Venereologica, 2016)
Psoriasis is a common, and currently incurable chronic immune-mediated skin disease, with incompletely understood etiology partially due to the unavailability of animal models that can emulate major features of the disease.