Buscar
Mostrando ítems 1-10 de 17
Dorsal root ganglion neurons and tyrosine hydroxylase: An intriguing association with implications for sensation and pain
(Elsevier Science, 2016-02)
Tyrosine hydroxylase (TH) is a rate-limiting enzyme broadly expressed in noradrenergic and dopaminergic neurons in the central nervous system.57,70 Tyrosine hydroxylase is also expressed by peripheral sympathetic neurons98 ...
A Sensory Neuron Subpopulation with Unique Sequential Survival Dependence on Nerve Growth Factor and Basic Fibroblast Growth Factor during Development
(Society for Neuroscience, 2001-11)
We characterized a subpopulation of dorsal root ganglion (DRG) sensory neurons that were previously identified as preferential targets of enkephalins. This group, termed P-neurons after their “pear” shape, sequentially ...
The same cellular signaling pathways mediate survival in sensory neurons that switch their trophic requirements during development
(Wiley Blackwell Publishing, Inc, 2003-06)
A distinct subpopulation of rat dorsal root sensory (DRG) neurons, termed P-neurons, switch their trophic requirements for survival during development from nerve growth factor (NGF) at embryonic stages to basic fibroblast ...
Autonomic neural signals in bone: Physiological implications for mandible and dental growth
(Pergamon-Elsevier Science Ltd, 2004-06)
Signals derived from the autonomic nervous system exert potent effects on osteoclast and osteoblast function. A ubiquitous sympathetic and sensory innervation of all periosteal surfaces exists and its disruption affects ...
Cutaneous inflammation regulates THIK1 expression in small C-like nociceptor dorsal root ganglion neurons
(Academic Press Inc Elsevier Science, 2017-09)
Tandem pore-domain Halothane Inhibited K+ channel (THIK1) is a two-pore-domain potassium channel (K2P) present in dorsal root ganglia (DRG). We previously demonstrated that THIK1 mRNA levels in the DRG dropped ipsilaterally ...
Lrig1 and lrig3 cooperate to control ret receptor signaling, sensory axonal growth and epidermal innervations
(Company of Biologists, 2021-08)
Negative feedback loops represent a regulatory mechanism that guarantees that signaling thresholds are compatible with a physiological response. Previously, we established that Lrig1 acts through this mechanism to inhibit ...
Positional differences of axon growth rates between sensory neurons encoded by runx3
(Nature Publishing Group, 2012-09)
The formation of functional connectivity in the nervous system is governed by axon guidance that instructs nerve growth and branching during development, implying a similarity between neuronal subtypes in terms of nerve ...
Expression of vesicular glutamate transporters in sensory and autonomic neurons innervating the mouse urinary bladder
(Elsevier, 2013-07)
Purpose: Vesicular glutamate transporters (VGLUTs), essential for loading glutamate into synaptic vesicles, are present in various neuronal systems. However, the expression of VGLUTs in neurons innervating the urinary ...
Tetraspanin1 promotes NGF signaling by controlling TrkA receptor proteostasis
(Birkhauser Verlag Ag, 2019-09)
The molecular mechanisms that control the biosynthetic trafficking, surface delivery, and degradation of TrkA receptor are essential for proper nerve growth factor (NGF) function, and remain poorly understood. Here, we ...
Distribution and characterization of nitric oxide synthase in the nervous system of Triatoma infestans (insecta: heteroptera)
(Springer Heidelberg, 2007)
The biochemical characterization of nitric oxide synthase (NOS) and its distribution in the central nervous system (CNS) were studied in the heteropteran bug Triatoma infestans. NOS-like immunoreactivity was found in the ...