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Genetic Analysis of Signal Peptides in Amphibian Antimicrobial Secretions
(Indian Academy of Sciences, 2018-12)
Amphibian secretion is an important source of bioactive molecules that naturally protect the skin against noxious microorganisms. Collectively called antimicrobial peptides (AMPs), these molecules have a wide spectrum of ...
A combined prediction strategy increases identification of peptides bound with high affinity and stability to porcine MHC class I molecules SLA-1*04:01, SLA-2*04:01, and SLA-3*04:01
(Springer, 2016-02)
Affinity and stability of peptides bound by major histocompatibility complex (MHC) class I molecules are important factors in presentation of peptides to cytotoxic T lymphocytes (CTLs). In silico prediction methods of ...
Identification and characterization of antioxidant peptides obtained from the bioaccessible fraction of α-lactalbumin hydrolysate
(Wiley Blackwell Publishing, Inc, 2021-10)
Abstract: Whey is an abundantand sustainable source of bioactive peptides obtained from cheese making process. Whey proteins such as α-lactalbumin can be biologically active when the bioactive peptides encrypted in the ...
Towards High-throughput Immunomics for Infectious Diseases: Use of Next-generation Peptide Microarrays for Rapid Discovery and Mapping of Antigenic Determinants
(American Society for Biochemistry and Molecular Biology, 2015-04)
Complete characterization of antibody specificities associated to natural infections is expected to provide a rich source of serologic biomarkers with potential applications in molecular diagnosis, follow-up of chemotherapeutic ...
Production and evaluation of chicken antibodies against a synthetic peptide from glial growth factor.
(Universidad del Zulia, 2013)
Identification of renin inhibitors peptides from amaranth proteins by docking protocols
(Elsevier, 2020-01)
The objective of this work was to develop a new protocol to predict with greater confidence peptides as potential inhibitors of the renin enzyme. For this, free, friendly and rigorous servers developed specifically for ...
Synergistic and antibiofilm activity of the antimicrobial peptide P5 against carbapenem-resistant Pseudomonas aeruginosa
(Elsevier Science, 2019-07)
In the search for new antimicrobial molecules, antimicrobial peptides (AMPs) offer a viable alternative to conventional antibiotics, as they physically disrupt the bacterial membranes, leading to membrane disruption and ...
Cleavage of Peptides from Amphibian Skin Revealed by Combining Analysis of Gland Secretion and in Situ MALDI Imaging Mass Spectrometry
(American Chemical Society, 2018-05)
Peptides from skin secretions of amphibians are considered important components of their immune system and also play a relevant role in their defense mechanism against predators. Herein, by using mass spectrometry (MS), ...
A QM/MM study of the molecular recognition site of bapineuzumab toward the amyloid-β peptide isoforms
(Taylor & Francis Ltd, 2016-02)
The molecular mechanism of recognition of amyloid-beta (Aβ) peptide isoforms by bapineuzumab was studied using a quantum mechanics and molecular mechanics (QM/MM) method. In this work, geometric optimisations were performed ...
Conformational and electronic study of cis-peptides (non-proline residues) occurring in natural proteins
(Elsevier Science, 2009-03)
First-principle computations were carried out on the conformational hyperspace of cis-peptide bond isomers of Ac-Gly-Gly-NHMe, Ac-Gly-Ala-NHMe, Ac-Ala-Gly-NHMe and Ac-Ala-Ala-NHMe. Using the concept of multidimensional ...