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Autophagy in development, cell differentiation, and homeodynamics: From molecular mechanisms to diseases and pathophysiology
(Hindawi Publishing Corporation, 2014-01)
The focus of this special issue is to highlight the role of autophagy in cellular homeodynamics, cell differentiation, and development with an outlook to diseases. Autophagy is an evolutionarily conserved catabolic process ...
Streptozotocin-Induced Diabetes Models: Pathophysiological Mechanisms and Fetal Outcomes
(Hindawi Publishing Corporation, 2014-01-01)
Glucose homeostasis is controlled by endocrine pancreatic cells, and any pancreatic disturbance can result in diabetes. Because 8% to 12% of diabetic pregnant women present with malformed fetuses, there is great interest ...
Hypotension caused by therapeutic doses of venlafaxine: case report and proposed pathophysiological mechanisms
(SAGE PUBLICATIONS LTD, 2008)
Although venlafaxine is usually associated with modest increases in blood pressure and not so often clinical hypertension, there are a few reported cases of hypotension related to overdoses of this specific antidepressant. ...
Remote Cerebellar Hemorrhage (Zebra Sign) in Vascular Neurosurgery: Pathophysiological Insights
(JAPAN NEUROSURGICAL SOC, 2009)
Hemorrhage in regions remote from the site of initial intracranial operations is rare, but may be fatal. Postoperative cerebellar hemorrhage as a complication of supratentorial surgery, with a radiological appearance known ...
Pathophysiology of vascular remodeling in hypertension
(Hindawi Publishing Corporation, 2013-07)
Vascular remodeling refers to alterations in the structure of resistance vessels contributing to elevated systemic vascular resistance in hypertension. We start with some historical aspects, underscoring the importance of ...
Pathophysiology of mesenteric ischemia/reperfusion: a review.
(2005-07-01)
During ischemia, the cell structures are progressively damaged, but restoration of the blood flow, paradoxically, intensifies the lesions caused by the ischemia. The mechanisms of ischemia injury and reperfusion (I/R) have ...
Pathogenesis of napkin dermatitis - Part I
(SOC BRASILEIRA DERMATOLOGIA, 2008)
Irritant contact dermatitis is the most prevalent diaper dermatitis and, probably, the most common cause of skin disease in infancy. The wearing of diaper leads to overhydration, increased local temperature and humidity. ...
Physiological and pathophysiological factors affecting the expression and activity of the drug transporter MRP2 in intestine: Impact on its function as membrane barrier
(Academic Press Ltd - Elsevier Science Ltd, 2016-07)
The gastrointestinal epithelium functions as a selective barrier to absorb nutrients, electrolytes and water, but at the same time restricts the passage into the systemic circulation of intraluminal potentially toxic ...
Lesões intestinais decorrentes de isquemia e reperfusão: Fisiopatologia e modelos experimentais
(2005-06-01)
The intestinal ischemia is unusual in vascular surgery emergency. Its main causes are embolisms and arterial thrombosis. In addition to severe ischemia, reperfusion of the ischemic tissues can lead to several complications ...