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Cardiorespiratory and neuroendocrine changes induced by methadone in conscious and in isoflurane anaesthetised dogs
(Elsevier B.V., 2012-12-01)
The aim of this study was to compare the cardiorespiratory and neurohormonal effects of methadone in conscious and in isoflurane anaesthetised dogs. Six mature dogs (28.0 +/- 3.8 kg bodyweight) received intravenous (IV) ...
Effects of methadone, alone or in combination with acepromazine or xylazine, on sedation and physiologic values in dogs
(Wiley-Blackwell, 2008-11-01)
Objective To evaluate the effects of methadone, administered alone or in combination with acepromazine or xylazine, on sedation and on physiologic values in dogs.Study design Randomized cross-over design.Animals Six adult ...
Comparison of the effects of epidural or intravenous methadone on the minimum alveolar concentration of isoflurane in dogs
(Elsevier B.V., 2012-06-01)
The effects of epidural and intravenous (IV) methadone (0.5 mg/kg) on the minimum alveolar concentration of isoflurane (ISOMAC) were compared in dogs. Six dogs (16.5 +/- 2.5 kg bodyweight) received three treatments in ...
Determination of the sevoflurane sparing effect of methadone in cats
(Wiley-Blackwell, 2011-07-01)
Objective To determine the magnitude and duration of sevoflurane minimum alveolar concentration (MAC) reduction following a single intravenous (IV) dose of methadone in cats.Study design Prospective experimental study.Animals ...
Efeitos sedativo e cardiorrespiratório da administração da metadona, isoladamente ou em associação à acepromazina ou xilazina, em gatos
(2008-12-01)
Six cats weighting 3.3±0.3 kg were randomly allocated to 6 treatments, with at least one-week intervals. The cats received intramuscular administration of physiological saline (control), methadone (0.3 mg/ kg), acepromazine ...
Plasma concentrations and behavioral, antinociceptive, and physiologic effects of methadone after intravenous and oral transmucosal administration in cats
(Amer Veterinary Medical Assoc, 2011-06-01)
Objective-To determine plasma concentrations and behavioral, antinociceptive, and physiologic effects of methadone administered via IV and oral transmucosal (OTM) routes in cats.Animals-8 healthy adult cats.Procedures-Methadone ...
Effects of methadone on the minimum alveolar concentration of isoflurane in dogs
(Wiley-Blackwell, 2010-05-01)
Objective To investigate the effects of methadone on the minimum alveolar concentration of isoflurane (ISO(MAC)) in dogs.Study design Prospective, randomized cross-over experimental study.Animals Six adult mongrel dogs, ...
Comparative study on the sedative effects of morphine, methadone, butorphanol or tramadol, in combination with acepromazine, in dogs
(Wiley-Blackwell Publishing, Inc, 2009-01-01)
To compare the effects of morphine (MOR), methadone (MET), butorphanol (BUT) and tramadol (TRA), in combination with acepromazine, on sedation, cardiorespiratory variables, body temperature and incidence of emesis in ...
Comparison of the cardio-respiratory effects of methadone and morphine in conscious dogs
(Wiley-Blackwell Publishing, Inc, 2009-08-01)
The effects of methadone and morphine were compared in conscious dogs. Six animals received morphine sulfate (1 mg/kg) or methadone hydrochloride (0.5 mg/kg [MET0.5] or 1.0 mg/kg [MET1.0]) intravenously (i.v.) in a randomized ...
Effects of subcutaneous methadone, morphine, buprenorphine or saline on thermal and pressure thresholds in cats
(Blackwell Publishing, 2006-12-01)
This study compared pressure and thermal thresholds after administration of three opioids in eight cats. Pressure stimulation was performed via a bracelet taped around the forearm. Three ball-bearings were advanced against ...