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Endothelium-dependent coronary flow in ischemia reperfusion
(Gustav Fischer VerlagJenaAlemanha, 1997)
Force patterns of hypoxic myocardium applied to oxygenated muscle preparations: Comparison with effects of regional ischemia on the contraction of non-ischemic myocardium
(1996-12-01)
Objective: To examine the basis for local wall motion abnormalities commonly seen in patients with ischemic heart disease, computer-controlled isolated muscle studies were carried out. Methods: Force patterns of physiologically ...
Effect of atenolol pre-treatment in heart damage in a model of intestinal ischemia-reperfusion
(2017-11-01)
Purpose: To investigate the effects of atenolol in inflammatory mediator and oxidative stress in a myocardial injury by intestinal ischemia/reperfusion in rat model. Methods: Adult Wistar male rats were randomly (n=8), ...
Parecoxib reduces renal injury in an ischemia/reperfusion model in rats
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2015-04-01)
To evaluate the effect of parecoxib (an NSAID) on renal function by measuring plasma NGAL (serum neutrophil gelatinase-associated lipocalin) levels in an induced-ischemia rat model. METHODS: Forty male Wistar rats were ...
Heart injury following intestinal ischemia reperfusion in rats is attenuated by association of ischemic preconditioning and adenosine
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2014-01-01)
PURPOSE: To investigate the effect of ischemic preconditioning (IPC) and adenosine as strategies to protect cardiac injury caused by intestinal IR in rats, based on increasing in adenosine bioavailability and improvement ...
CaMKII-dependent responses to ischemia and reperfusion challenges in the heart
(Frontiers, 2014-05)
Ischemic heart disease is a leading cause of death, and there is considerable imperative to identify effective therapeutic interventions. Cardiomyocyte Ca2+ overload is a major cause of ischemia and reperfusion injury, ...
Sudden cardiac death athletes: a systematic review
(2010-08-03)
Previous events evidence that sudden cardiac death (SCD) in athletes is still a reality and it keeps challenging cardiologists. Considering the importance of SCD in athletes and the requisite for an update of this matter, ...
Insulin/NFkB protects against ischemia-induced necrotic cardiomyocyte death
(Elsevier, 2015)
In the heart, insulin controls key functions such as metabolism, muscle contraction and cell death.
However, all studies have been focused on insulin action during reperfusion. Here we explore the cardioprotective
action ...
Potential Therapies to Protect the Aging Heart Against Ischemia/Reperfusion Injury
(Frontiers Media, 2021)
Despite important advances in the treatment of myocardial infarction that have significantly reduced mortality, there is still an unmet need to limit the infarct size after reperfusion injury in order to prevent the onset ...