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The role of cytokines in inflammatory bone loss
(2013-09-12)
Chronic inflammatory processes close to bone often lead to loss of bone in diseases such as rheumatoid arthritis, periodontitis, loosened joint prosthesis and tooth implants. This is mainly due to local formation of bone ...
Cytokine profile of Ehrlich ascites tumor treated with Bothrops jararaca venom
(2002-08-01)
WE previously demonstrated that Bothrops jararaca venom (BjV) has an antitumor effect on Ehrlich ascites tumor (EAT) cells and induces an increase of polymorphonuclear leukocytes in early stages of tumor growth. It has ...
Interleukin-4 and interleukin-13 inhibit the expression of leukemia inhibitory factor and interleukin-11 in fibroblasts
(Pergamon-Elsevier B.V. Ltd, 2012-01-01)
Cytokines produced by inflammatory or resident mesenchymal cells play important modulatory roles in the pathogenesis of inflammation induced bone loss. In the present study, the effects of IL-4 and IL-13 on the expression ...
Structure and function of interleukin-22 and other members of the interleukin-10 family
(Birkhauser VerlagBasel, 2010-09)
The IL-10 family of cytokines is comprised of IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, and IFN-λs (IL-28A, IL-28B, and IL-29). The IL-10 family members bind to shared class II cytokine receptor chains that associate in ...
Immunopathogenesis of reactive arthritis: role of the cytokines
(Baishideng Publishing Group, 2014-07)
Reactive arthritis (ReA), also known as postinfectious arthritis, belongs to the group of related arthropathies known as spondyloarthritis (SpA). ReA can arise 1-4 weeks after a gastrointestinal or genitourinary infection, ...
The role of interleukin-10 in the differential expression of interleukin-12p70 and its beta 2 receptor on patients with active or treated paracoccidioidomycosis and healthy infected subjects
(Elsevier B.V., 2005-01-01)
Paracoccidioidomycosis patients present an antigen-specific Th1 immunosuppression. To better understand this phenomenon, we evaluated the interleukin (IL)-12 pathway by measuring IL-12p70 production and CD3(+) T cell ...
Sialidase activity in aerobic vaginitis is equal to levels during bacterial vaginosis
(2013-04-01)
Objective: To evaluate levels of proinflammatory cytokines and sialidase activity in aerobic vaginitis (AV) in relation to normal vaginal flora and bacterial vaginosis (BV). Study design: In this cross-sectional study, a ...
Cytokine gene variants and venous thrombotic risk in the BRATROS (BRAZILIAN THROMBOSIS STUDY)
(2007-05-21)
Introduction: Venous thrombosis (VT) and inflammation are two closely related entities. In the present investigation we assessed whether there is a relation between genetic modifiers of the inflammatory response and the ...
Interleukin-10 but not interleukin-18 may be associated with the immune response against well-differentiated thyroid cancer
(Hospital Clinicas, Univ Sao PauloSao PauloBrasil, 2011)
Role of natural killer cells in antitumor resistance
(2005-12-01)
Natural killer cells constitute a population of lymphocytes able to non-specifically destroy virus-infected and some kinds of tumor cells. Since this lytic activity was shown by non-immunized animals the phenomenon is ...