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Histological maturation of astroglial cells in the archicortex of young hypothyroid rats
(1988)
The maturation of fibrous astrocytes was studied in the archicortex (hippocampus) of rats rendered hypothyroid by perinatal administration of propylthiouracil (PTU). A decrease in the number of protoplasmic processes and ...
Neuronal lactate levels depend on glia-derived lactate during high brain activity in Drosophila
(John Wiley and Sons Inc.P.O.Box 18667NewarkNJ 07191-8667, 2020)
Chaski, a novel drosophila lactate/pyruvate transporter required in glia cells for survival under nutritional stress
(Nature Publishing Group, 2018)
The intercellular transport of lactate is crucial for the astrocyte-to-neuron lactate shuttle (ANLS), a model of brain energetics according to which neurons are fueled by astrocytic lactate. In this study we show that the ...
Re-establishment of direct synaptic connections between sensory axons and motoneurons after lesions of neonatal opossum CNS (Monodelphis domestica) in culture
(1998)
For functional recovery after spinal cord injury, regenerating fibres need to grow and to reform appropriate connections with their targets. The isolated central nervous system of neonatal opossums aged 1-9 days has been ...
Effects of interleukin-1β on spinal cord nociceptive transmission in intact and propentofylline-treated rats
(2007)
To investigate the contribution of glial cells in the spinal cord nociceptive transmission, the effect of intrathecally administered interleukin-1β (IL-1β) was studied in rats treated with the glial cell inactivator ...
Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study
(Springer, 2015)
Neurodegenerative diseases of the central nervous system are characterized by pathogenetic cellular and molecular changes in specific areas of the brain that lead to the dysfunction and/or loss of explicit neuronal ...
Glutathione Transferase-M2-2 Secreted from Glioblastoma Cell Protects SH-SY5Y Cells from Aminochrome Neurotoxicity
(Springer, 2015)
U373MG cells are able to take up aminochrome that induces glutathione transferase M2-2 (GSTM2) expression in a concentration-dependent manner where 100 A mu M aminochrome increases GSTM2 expression by 2.1-fold (P < 0.001) ...
Alzheimer's Disease-Like Pathology Triggered by Porphyromonas gingivalis in Wild Type Rats Is Serotype Dependent
(Frontiers Media, 2020)
Periodontal disease is a disease of tooth-supporting tissues. It is a chronic disease with inflammatory nature and infectious etiology produced by a dysbiotic subgingival microbiota that colonizes the gingivodental sulcus. ...
Current advances in comprehending dynamics of regenerating axons and axon-glia interactions after peripheral nerve injury in zebrafish
(MDPI, 2021)
Following an injury, axons of both the central nervous system (CNS) and peripheral nervous system (PNS) degenerate through a coordinated and genetically conserved mechanism known as Wallerian degeneration (WD). Unlike ...