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The importance of drug repurposing in the field of antiepileptic drug development
(Springer, 2016)
Drug repurposing involves finding new therapeutic uses for existing drugs, including marketed, discontinued, shelved, and investigational drugs. The advantages of this strategy are many: reduced drug development timeline, ...
Drug repositioning: current approaches and their implications in the precision medicine era
(Taylor & Francis, 2018-01)
Introduction: Drug repositioning implies finding new medical uses for existing drugs. It represents a cost-efficient approach, since the new indications are built on the basis of available information on pharmacokinetics, ...
Challenges and opportunities with drug repurposing: finding strategies to find alternative uses of therapeutics
(Informa Healthcare, 2019-12)
Drug repurposing(or repositioning) implies finding new therapeutic indications for existingdrugs (including approved, failed, discontinued and experimental drugs), andrepresents a substantial percentage of recent drug ...
In silico drug repositioning for chagas disease
(Bentham Science Publishers, 2020)
Chagas disease is an infectious tropical disease included within the group of neglected tropical diseases. Though historically endemic to Latin America, it has lately spread to high-income countries due to human migration. ...
In silico REPOSITIONING OF NEW DRUGS AGAINST Schistosoma mansoni
(Universidade Federal de Goiás, 2018)
User-centered design improves the usability of drug-drug interaction alerts: Experimental comparison of interfaces
(Academic Press Inc Elsevier Science, 2017-02)
Clinical Decision Support Systems can alert health professionals about drug interactions when they prescribe medications. The Hospital Italiano de Buenos Aires in Argentina developed an electronic health record with drug-drug ...
Pharmacological approaches towards rationalizing the use of endoparasitic drugs in small animals
(Wiley Blackwell Publishing, Inc, 2006-12)
Parasitic diseases are an important health concern to small animal veterinarians worldwide, and their zoonotic potential is also of relevance to human medicine. The treatment and control of such conditions relies heavily ...
Lifetime use of psychedelics is associated with better mental health indicators during the COVID-19 pandemic
(AKJournals, 2021-05-04)
Background and aimsThe COVID-19 pandemic and its consequences represent a major challenge to the mental health and well-being of the general population. Building on previous work on the potential long-term benefits of ...
Interfacial stabilization of the antitumoral drug Paclitaxel in monolayers of GM1 and GD1a gangliosides
(Elsevier Science, 2015-06)
Molecular interactions between the anti-cancer agent Paclitaxel (Ptx), and two gangliosides with different sialic acid content, GM1 and GD1a, were investigated using the Langmuir film balance technique. Ptx showed interfacial ...
Mecanismos de acción farmacológica
(Servicio Nacional de Aprendizaje (SENA)Centro Nacional de Servicios Hospitalarios., 2019)