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Induction of ischemic tolerance as a promising treatment against diabetic retinopathy
(Medknow Publications, 2014-09)
Diabetic retinopathy is a leading cause of acquired blindness, and it is the most common ischemic disorder of the retina. Available treatments are not very effective. Efforts to inhibit diabetic retinopathy have focused ...
Real-time diabetic retinopathy patient screening using multiscale AM-FM methods
(Institute of Electrical and Electronics Engineers, 2012-10)
n this paper we present a robust and improved system for diabetic retinopathy (DR) screening. The goal of the system is to automatically screen out digital fundus photographs of diabetic patients who do not present signs ...
Proliferative retinopathy and neovascularization of the anterior segment in female type 2 diabetic rats
(BioMed Central, 2013-11)
Background: To examine the presence of diabetic retinopathy in a female rat model of type 2 diabetes fed on a high-fat diet (HFD). Methods: Wistar rats were injected with streptozotocin (STZ) at the age of two days and fed ...
Diabetic retinopathy: could the alpha-1 antitrypsin be a therapeutic option?
(BioMed Central, 2014-11)
Diabetic retinopathy is one of the most important causes of blindness. The underlying mechanisms of this disease include inflammatory changes and remodeling processes of the extracellular-matrix (ECM) leading to pericyte ...
Detection of diabetic retinopathy based on a convolutional neural network using retinal fundus images
(Springer Verlag, 2017)
Diabetic retinopathy is one of the leading causes of blindness. Its damage is associated with the deterioration of blood vessels in retina. Progression of visual impairment may be cushioned or prevented if detected early, ...
Detection of exudates in diabetic retinopathy images using boosting based algorithms
(Mattingley PublishingUS, 2020-06-12)
ABSTRACT
Diabetic retinopathy is a leading cause of vision loss in developed countries. Regular diabetic retinal eye screenings are needed to detect early signs of retinopathy, so that appropriate treatments can be rendered ...
Can a simple test of functional capacity add to the clinical assessment of diabetes?
(Wiley, 2015)
AIM: To identify impairment in functional capacity associated with complicated and non-complicated diabetes using the 6-min walk distance test. METHODS: We enrolled 111 adults, aged >/=40 years, with Type 2 diabetes from ...
Elucidating the mechanism of action of alpha-1-antitrypsin using retinal pigment epithelium cells exposed to high glucose: Potential use in diabetic retinopathy
(Public Library of Science, 2020-02)
Background: Alpha-1-antitrypsin is a protein involved in avoidance of different processes that are seen in diabetic retinopathy pathogenesis. These processes include apoptosis, extracellular matrix remodeling and damage ...
Role of ω3 polyunsaturated fatty acids in diabetic retinopathy: A morphological and metabolically cross talk among blood retina barriers damage, autoimmunity and chronic inflammation
(BioMed Central, 2019-05-15)
Vision disorders are one of the most serious complications of diabetes mellitus (DM) affecting the quality of life of patients and eventually cause blindness. The ocular lesions in diabetes mellitus are located mainly in ...
The rs4712527 Polymorphism in the CDKAL1 Gene: A protective factor for proliferative diabetic retinopathy progress in type 2 diabetes
(SAGE Publications, 2018-05)
Purpose: Diabetic retinopathy (DR) is one of the chronic retinal disorders linked to diabetes and remains the leading cause of blindness in working-age people. Many studies have demonstrated the existence of associations ...