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Paradoxical effects of cytokines in tumor immune surveillance and tumor immune escape
(2007)
The role of cytokines in modulating the formation of new tumors is mediated by their ability to regulate antigen-specific anti-tumor responses and by the activation of non-specific mechanisms, including those involved in ...
Expression Suppression and Activity Inhibition of TRPM7 Regulate Cytokine Production and Multiple Organ Dysfunction Syndrome During Endotoxemia: a New Target for Sepsis
(NLM (Medline), 2019)
Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.BACKGROUND: Main pathological features detected during sepsis and endotoxemia include over-secretion of pro-inflammatory ...
Peripheral cytokine profile in Chilean patients with Crohn's disease and ulcerative colitis
(2009)
Crohn's disease (CD) and ulcerative colitis (UC) belong to the group of inflammatory bowel diseases (IBD), with complex ethiopathogenic factors that include an unbalanced immune and inflammatory response to commensal and ...
Ex vivo infection of human placental chorionic villi explants with Trypanosoma cruzi and Toxoplasma gondii induces different Toll-like receptor expression and cytokine/chemokine profiles
(Wiley, 2017-07)
ProblemTrypanosoma cruzi and Toxoplasma gondii present, respectively, low and high congenital transmission rates. The placenta as an immune regulatory organ expresses TLRs, leading to the secretion of cytokines. Both ...
Human periodontal ligament fibroblasts synthesize C-reactive protein and Th-related cytokines in response to interleukin (IL)-6 trans-signalling
(Blackwell, 2018)
Aim
To characterize the potential of human periodontal ligament fibroblasts (HPLF) to synthesize CRP and Th-related cytokines in response to IL-6 in periodontal health and apical inflammation.
Matrix metalloproteinases regulate extracellular levels of SDF-1/CXCL12, IL-6 and VEGF in hydrogen peroxide-stimulated human periodontal ligament fibroblasts
(Elsevier, 2015)
Periodontitis is a highly prevalent infectious disease characterized by the progressive inflammatory
destruction of tooth-supporting structures, leading to tooth loss. The underling molecular mechanisms
of the disease ...
Interleukin-21 expression and its association with proinflammatory cytokines in untreated chronic periodontitis patients
(2012)
Background: Interleukin-21 (IL-21) controls the differentiation of T-helper Th17 cells and induces the production of IL-17
in this T-cell subtype. The aim of this study is to determine the
relative expression of IL-21 ...
Local and systemic liberation of cytokines in ulcerative colltis
(1997)
Determination of plasmatic and tissular cytokine concentrations in inflammatory bowel diseases have frequently resulted in conflicting data. The aim of this study is to determine, in patients with ucerative colitis (UC), ...
T helper 1/T helper 2 cytokine imbalance in respiratory syncytial virus infection is associated with increased endogenous plasma cortisol
(AMER ACAD PEDIATRICS, 2006-05)
OBJECTIVE. Cellular immunity has classically been described as the defense mechanism for viral infections. The development of cellular or humoral immune responses will depend on a repertoire of cytokines produced by numerous ...