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cAMP-PKA signal transduction specificity in Saccharomyces cerevisiae
(Springer, 2020-09)
Living cells have developed a set of complex signaling responses, which allow them to withstand different environmental challenges. Signaling pathways enable the cell to monitor external and internal states and to articulate ...
Hydrogen sulphide as a guard cell network regulator
(Wiley Blackwell Publishing, Inc, 2020-11-29)
Hydrogen sulphide (H2S) is an endogenously produced gasotransmitter that has rapidly emerged as an active signalling component of several plant processes, stomatal movement regulation among them. The guard cells (GCs), ...
New insights into the control of neurotrophic growth factor receptor signaling: Implications for nervous system development and repair
(Wiley Blackwell Publishing, Inc, 2012-12)
Neurotrophic growth factors control neuronal development by activating specific receptor tyrosine kinase positive signaling pathways, such as Ras-MAPK and PI3K-Akt cascades. Once activated, neurotrophic factor receptors ...
Push-Pull and Feedback Mechanisms Can Align Signaling System Outputs with Inputs
(Cell Press, 2016-11)
Many cell signaling systems, including the yeast pheromone response system, exhibit “dose-response alignment” (DoRA), in which output of one or more downstream steps closely matches the fraction of occupied receptors. DoRA ...
The shade-avoidance syndrome: Multiple signals and ecological consequences
(Wiley Blackwell Publishing, Inc, 2017-01)
Plants use photoreceptor proteins to detect the proximity of other plants and to activate adaptive responses. Of these photoreceptors, phytochrome B (phyB), which is sensitive to changes in the red (R) to far-red (FR) ratio ...
Retrograde bone morphogenetic protein signaling shapes a key circadian pacemaker circuit
(Society For Neuroscience, 2013-01)
The neuropeptide pigment-dispersing factor (PDF) synchronizes molecular oscillations within circadian pacemakers in the Drosophila brain. It is expressed in the small ventral lateral neurons (sLNvs) and large ventral lateral ...
Molecular Basis of Redox Signaling
(Landes Bioscience, 2019-05)
Oxidants are produced in physiological and pathological conditions. The production of reactive nitrogen and oxygen species (RNS and ROS, respectively) can lead to vastly different cellular outcomes depending on their ...
Interaction of p53 with tumor suppressive and oncogenic signaling pathways to control cellular reactive oxygen species production
(Mary Ann Liebert, 2011-09)
p53 is a crucial transcription factor with tumor suppressive properties that elicits its function through specific target genes. It constitutes a pivotal system that integrates information received by many signaling pathways ...
A novel time stamping data acquisition system using a digital oscilloscope for single counting photons
(Institute of Electrical and Electronics Engineers Inc., 2017-12)
In this paper we present an algorithm of signal processing that allows the use of a PC-based oscilloscope in order to count events with a time stamping register. This novel application has a direct use on recording of ...
Cross-talk between mitochondrial function, growth, and stress signalling pathways in plants
(Oxford University Press, 2020-12)
Plant mitochondria harbour complex metabolic routes that are interconnected with those of other cell compartments and changes in mitochondrial function remotely influence processes in different parts of the cell. This ...