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Homogenates of skeletal muscle injected with snake venom inhibit myogenic differentiation in cell culture
(2013-02)
Introduction: Viperid snakebite envenomings are characterized by muscle necrosis and a deficient regenerative response. Methods: Homogenates from gastrocnemius muscles of mice injected with the venom of the snake Bothrops ...
Differential susceptibility of C2C12 myoblasts and myotubes to group II phospholipase A2 myotoxins from crotalid snake venoms
(2005)
Group II phospholipase A2 (PLA2) myotoxins isolated from Viperidae/Crotalidae snake venoms induce a rapid cytolytic
effect upon diverse cell types in vitro. Previous studies suggested that this effect could be more ...
Skeletal muscle degeneration induced by venom phospholipases A2: insights into the mechanisms of local and systemic myotoxicity
(2003-12)
Local and systemic skeletal muscle degeneration is a common consequence of envenomations due to snakebites and mass bee attacks. Phospholipases A2 (PLA2) are important myotoxic components in these venoms, inducing a similar ...
Meiotic Chromosome Behavior and Capsule Setting in Doritaenopsis Hybrids
(J. AMER. SOC. HORT. SCI. 133(1):107–116. 2008, 2008-10-06)
The development of new cultivars in Doritaenopsis Guillaum. & Lami orchids is often hindered by factors such as low seed count in hybrids. Cytological study may offer the ability to develop new hybrids by revealing cultivars ...
Balanced dynamics of deep and shallow Hadley circulations in the tropics
(Journal of Advances in Modeling Earth Systems 6(3): 777-804, 2014-05-06)
This paper examines the dynamics of large-scale overturning circulations in the tropical atmosphere using an idealized zonally symmetric model on the equatorial b-plane. Under certain simplifications of its coefficients, ...
Lemnitoxin, the major component of Micrurus lemniscatus coral snake venom, is a myotoxic and pro-inflammatory phospholipase A2
(2016-08-26)
The venom of Micrurus lemniscatus, a coral snake of wide geographical distribution in South America, was fractionated by reverse-phase HPLC and the fractions screened for phospholipase A2 (PLA2) activity. The major component ...
Norrie Disease Gene Mutation in a Large Costa Rican Kindred With a Novel Phenotype Including Venous Insufficiency
(1997)
A large Costa Rican kindred has been identified with 15 males affected with congenital blindness, progressive hearing loss, and venous insufficiency. Due to ophthalmological and audio-otological findings, including bilateral ...
Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect
(2017-03-23)
Arthritis is a set of inflammatory conditions that induce aching, stiffness, swelling, pain and may cause functional disability with severe consequences to the patient’s lives. These are multi-mediated pathologies that ...