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Quantification of carbamazepine, carbamazepine-10,11-epoxide, phenytoin and phenobarbital in plasma samples by stir bar-sorptive extraction and liquid chromatography
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
A sensitive and reproducible stir bar-sorptive extraction and high-performance liquid chromatography-UV detection (SBSE/HPLC-UV) method for therapeutic drug monitoring of carbamazepine, carbamazepine-10,11-epoxide, phenytoin ...
Jacobsen catalyst as a P450 biomimetic model for the oxidation of an antiepileptic drug
(Elsevier Science BvAmsterdamHolanda, 2007)
Bioaccumulation and bioconcentration of carbamazepine and other pharmaceuticals in fish under field and controlled laboratory experiments. Evidences of carbamazepine metabolization by fish
(Elsevier Science, 2016-07)
There is a growing interest in evaluating the presence of pharmaceutical residues and their metabolites in aquatic biota. In this study, twenty pharmaceuticals, including carbamazepine (CBZ) and two metabolites, were ...
Chemometric resolution of fully overlapped capillary electrophoresis peaks: quantitation of carbamazepine in human serum in the presence of several interferences
(Wiley VCH Verlag, 2008-12)
Drug monitoring in serum samples was performed using second-order data generated by CE-DAD, processed with a suitable chemometric strategy. Carbamazepine could be accurately quantitated in the presence of its main metabolite ...
Usefulness of salivary drug monitoring for detectign efflux transporter overexpression
(Bentham Science Publishers, 2013-09)
Background: Bioavailability (F) and clearance (CL) are two pharmacokinetic parameters difficult to differentiate from simple plasma measurement when a drug is administered orally. Venous (V) / artery (A) concentration ratio ...
Identificação e determinação de fármacos ansiolíticos e antiepilépticos e seus metabólitos em efluente hospitalar
(Universidade Federal de Santa MariaBRQuímicaUFSMPrograma de Pós-Graduação em Química, 2012-12-06)
A new analytical methodology was developed in order to investigate the presence of five psychoactive
drugs (anxiolytic and antiepileptics), namely, bromazepam, carbamazepine, clonazepam, diazepam, and
lorazepam in the ...
Determinação de pesticidas organoclorados e fármacos em matrizes ambientais utilizando QuEChERS, extração líquido-líquido (LLE) e extração em fase sólida (SPE)
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Química - PPGQCâmpus São Carlos, 2021-11-24)
The presence of xenobiotic organic contaminants in water bodies, where arrive from releases of treated or untreated effluent, has raised concerns
about impacts related to the richness and biodiversity of aquatic life and ...
Estudio de genes candidatos sobre la efectividad y seguridad de la medicación anticonvulsiva en un grupo de pacientes colombianos afectados de epilepsia
(Departamento de FarmaciaUniversidad Nacional de Colombia - Sede Bogotá, 2019-03-13)
Objectives: to explore possible genetic determinants of response to anticonvulsant treatment in a group of Colombian epileptic patients.
Design: prospective cohort analytical observational study. We included 77 adult ...