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Remarkable Iodine-Catalyzed Synthesis of Novel Pyrrole- Bearing N-Polyaromatic β-Lactams
(Molecules, 2010-02-23)
The future of the β-lactams
(Current Biology, 2010-10)
In the 80 years since their discovery the β-lactam antibiotics have progressed through structural generations, each in response to the progressive evolution of bacterial resistance mechanisms. The generational progression ...
Recent approaches toward the generation of molecular diversity based on b-lactam structures
(Springer, 2017)
One of the most significant strategies in the search of biologically promising structures is the generation of scaffold diversity. Varying molecular scaffolds yielded useful small molecule tools for chemical genetic studies ...
Measurement of interaction parameters between glutathione and β-lactam antibiotics : a polarographic approach
(1988)
The interaction of glutathione with four β-lactam antibiotics was studied by an AC polarographic procedure. The interaction stability constant and the coordination number were calculated from the AC polarographic data. The ...
Synthesis of potentially bioactive PABA-related N-(aminoalkyl)lactamic amino acids and esters via selective SNAr reactions
(Springer, 2011-01-01)
Potentially bioactive N-(aminoalkyl)lactamic amino acids and esters were synthesized in satisfactory to good yields by SNAr reactions of aromatic acids with N-(3-aminopropyl)lactams followed by esterification with tertiary ...
Synthesis of potentially bioactive PABA-related N-(aminoalkyl)lactamic amino acids and esters via selective SNAr reactions
(Springer, 2011-01-01)
Potentially bioactive N-(aminoalkyl)lactamic amino acids and esters were synthesized in satisfactory to good yields by SNAr reactions of aromatic acids with N-(3-aminopropyl)lactams followed by esterification with tertiary ...
Novel beta-Lactams
(Contexto, 2008-10-01)
The beta-lactam class constitutes the largest group of antimicrobial agents, which includes penicillins, cephalosporins, monobactams, and carbapenems. These compounds, which have in common the beta-lactam ring in their ...
Effects of three γ-alkylidene-γ-lactams on the formation of multispecies biofilms
(Universidade Federal de Minas GeraisBrasilICA - INSTITUTO DE CIÊNCIAS AGRÁRIASUFMG, 2018-03-08)
A new approach for the thermodynamic modeling of the solubility of amino acids and ??-lactam compounds as a function of pH
(Fluid Phase Equilibria, 2013)