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Papel das células B e dos anticorpos na patogênese da hanseníase e das reações hansênicas
(BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM BIOQUÍMICA, 2017-04-28)
Leprosy is a spectral disease caused by Mycobacterium leprae infection. Subjects can
present single lesions with a reduced number of bacilli (paucibacillary - PB), but also
disseminated lesions and a high bacterial load ...
Determinación del proteoma de la cepa VCG-1 de Plasmodium Vivax y caracterización de moléculas candidatas para su inclusión en el desarrollo de una vacuna
(Universidad del RosarioDoctorado en Ciencias Biomédicas y BiológicasFacultad de Ciencias Naturales y Matemáticas, 2017)
Identifying and characterising proteins which use Plasmodium merozoites to invade host cells represents an important strategy for developing a method for controlling these parasites. However, basic P. vivax research has ...
Desenvolvimento de testes diagnósticos para Hepatite B baseados em imunossensores
(Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em Biotecnologia Industrial, 2017)
Autoantibody and environmental damage to the brain
(Universidad del RosarioDoctorado en Ciencias BiomédicasFacultad de Ciencias Naturales y Matemáticas, 2016)
Behavioral abnormalities and cognitive dysfunction may be present in patients with autoimmune diseases. The mechanisms that responsible for these neuropsychiatric manifestations are still largely unknown, however several ...
Caracterización del complejo mayor de histocompatibilidad clase II en primates del género Aotus
(Universidad del RosarioDoctorado en Ciencias BiomédicasFacultad de Ciencias Naturales y Matemáticas, 2017)
This work was aimed to contribute to increase our knowledge on the MHC class II in monkeys from the genus Aotus. Determining the sequences of MHC-DPA and MHC-DRA genes has allowed to complete the characterisation of the ...
Estudio de interacciones hospedero-patógeno y proteína-proteína en Plasmodium Vivax : evaluación de las proteínas del cuello de optrias -2, -4 y -5 y del antígeno apical de membrana-1
(Universidad del RosarioDoctorado en Ciencias BiomédicasFacultad de Ciencias Naturales y Matemáticas, 2018)
Malaria is one of the most important tropical diseases transmitted by vectors worldwide; Plasmodium vivax represents one of the most widely distributed species (affecting ~ 13.8 million people worldwide per year). Despite ...
Identificación de señales de selección natural en genes de Plasmodium vivax que codifican proteínas involucradas en el proceso de invasión para determinar su potencial uso en una vacuna antimalárica
(Universidad del RosarioDoctorado en Ciencias Biomédicas y BiológicasFacultad de Ciencias Naturales y Matemáticas, 2019)
Plasmodium vivax, an endoparasite that arose in Asia and spread around the world, has biomedical importance given that it is the second most important human-malaria parasite. Although efforts have been made to reduce the ...
Isolating and characterizing antimicrobial peptides derived from larvae of the blowfly Sarconesiopsis magellanica (diptera: Calliphoridae)
Larval therapy (LT) is an alternative treatment which uses fly larvae to heal chronic wounds; its action is based on debridement, bacterial removal and stimulating granulation tissue. The most important mechanism for ...
Caracterización funcional del canal de potasio activado por calcio de conductancia intermedia (KCa3.1) en el endotelio de la córnea en condiciones fisiológicas y en ambientes hiperglúcidos
The cornea is the lens that protects the anterior surface of the eye and its transparent nature is a crucial part of the functioning of the eye. This characteristic is mainly determined by the activity of the cells of its ...