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Standardization of a fluorescent-based quantitative adhesion assay to study attachment of Taenia solium oncosphere to epithelial cells in vitro
(Elsevier, 2012)
To fully understand the preliminary stages of Taenia solium oncosphere attachment in the gut, adequate tools and assays are necessary to observe and quantify this event that leads to infection. A fluorescent-based quantitative ...
Loss of prolyl hydroxylase-2 in myeloid cells and T-lymphocytes impairs tumor development
(Wiley, 2013)
The tumor microenvironment plays a pivotal role during cancer development and progression. The balance between suppressive and cytotoxic responses of the tumor immune microenvironment has been shown to have a direct effect ...
Early T follicular helper cell responses and germinal center reactions are associated with viremia control in immunized rhesus macaques
(American Society for Microbiology, 2019)
T follicular helper (T FH ) cells are fundamental in germinal center (GC) maturation and selection of antigen-specific B cells within secondary lymphoid organs. GC-resident T FH cells have been fully characterized in human ...
In vitro culture of spermatogonial stem cells isolated from adult alpaca (Vicugna pacos) testes analysed with Dolichos biflorus by flow cytometry.
(Wiley, 2019)
Spermatogonial stem cell (SSC) is known for its self-renewal capacity. We have studied the in vitro proliferation of isolated SSC from adult alpaca (Vicugna pacos) testes. A total of 107 samples were evaluated of which 31 ...
Sex-specific brain erythropoietin regulation of mouse metabolism and hypothalamic inflammation
(American Society for Clinical Investigation, 2020)
The blood hormone erythropoietin (EPO), upon binding to its receptor (EpoR), modulates high-fat diet-induced (HFO-induced) obesity in mice, improves glucose tolerance, and prevents white adipose tissue inflammation. ...
Axonal swellings and spheroids: a new insight into the pathology of neurocysticercosis
(Wiley, 2018)
Neurocysticercosis is a parasitic brain disease caused by the larval form (Cysticercus cellulosae) of the Taenia solium and is the leading cause of preventable epilepsy world-wide. However, the pathophysiology and relation ...
Mechanisms of liver fibrosis associated with experimental fasciola hepatica infection: Roles of Fas2 proteinase and hepatic stellate cell activation
(American Society of Parasitologists, 2011)
We have evaluated the possible mechanisms of liver fibrosis caused by Fasciola hepatica in an animal model and in culture using immortalized human stellate cells. Liver biopsies of F. hepatica-infected rats were performed ...
Insights into the role of B cells in the cortical pathology of Multiple sclerosis: evidence from animal models and patients
(Elsevier, 2021-05)
Multiple sclerosis (MS) is a chronic, immune-mediated disease of the central nervous system (CNS) that affects both white and gray matter. Although it has been traditionally considered as a T cell mediated disease, the ...
CHMP1A encodes an essential regulator of BMI1-INK4A in cerebellar development
(Springer Nature, 2012)
Charged multivesicular body protein 1A (CHMP1A; also known as chromatin-modifying protein 1A) is a member of the ESCRT-III (endosomal sorting complex required for transport-III) complex but is also suggested to localize ...
Polycystic echinococcosis in Pacas, Amazon Region, Peru
(Centers for Disease Control and Prevention, 2015)
In the Peruvian Amazon, paca meat is consumed by humans. To determine human risk for polycystic echinococcosis, we examined wild pacas from 2 villages; 15 (11.7%) of 128 were infected with Echinococcus vogeli tapeworms. ...