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Does slow embryo development predict a high aneuploidy rate on trophectoderm biopsy?
(Elsevier Sci Ltd, 2016)
The aneuploidy rates in expanded blastocysts biopsied on days 5 and 6 development were assessed in women undergoing IVF followed by array comparative genomic hybridization. This study included 1171 expanded blastocysts ...
Aneuploidy of chromosome 8 and C-MYC amplification in individuals from northern Brazil with gastric adenocarcinoma
(Int Inst Anticancer Research, 2005-11-01)
Background: Gastric cancer is the third most frequent type of neoplasia. In northern Brazil, the State of Para has a high incidence of this type of neoplasia. Limited data are available so far on the genetic events involved ...
CHROMOSOMAL CONSTITUTION IN ROB (5/15) GOAT PROGENY
(Elsevier B.V., 1994-12-01)
A total of 116 goats originating from three heterozygous bucks for rob (5/15) were cytogenetically studied at Botucatu, Brazil. In the mating 59,XY,t(5/15) x 60,XX, the offspring karyotype proportion did not differ ...
Genetic alterations in benign lesions: Chronic gastritis and gastric ulcer
(2006-01-28)
Aim: To investigate the occurrence of chromosome 3, 7, 8, 9, and 17 aneuploidies, TP53 gene deletion and p53 protein expression in chronic gastritis, atrophic gastritis and gastric ulcer, and their association with H pylori ...
Investigation of chromosome 21 aneuploidies in breast fibroadenomas by fluorescence in situ hybridisation
(Springer, 2006-12-01)
Fibroadenoma (FA) is a benign breast tumour that occurs in about 25% of women. Cytogenetic studies suggest that numerical chromosomal aberrations may contribute to tumorigenesis, but chromosomal instability is still poorly ...
Adaptation of image cytometry methodology for DNA ploidy analysis of cervical epithelium samples: A pilot study
(Taiwanese Journal of Obstetrics & Gynecology, 2018)
Aneuploidies, deletion, and overexpression of TP53 gene in intestinal metaplasia of patients without gastric cancer
(Elsevier B.V., 2004-09-01)
Gastric carcinogenesis is attributable to interacting environmental and genetic factors, through a sequence of events including intestinal metaplasia. Using a fluorescence in situ hybridization technique, we investigated ...
Apoptosis in different gastric lesions and gastric cancer: Relationship with Helicobacter pylori, overexpression of p53 and aneuploidy
(2007-11-19)
Apoptosis has an essential function in maintaining the integrity of the gastrointestinal mucosa. Its deregulation is associated with the occurrence of lesions such as in atrophic gastritis, peptic ulcers, intestinal ...
Tetrasomy 15Q11-Q13 identified by fluorescence in situ hybridization in a patient with autistic disorder
(2002-06-01)
We report a female child with tetrasomy of the 15q11-q13 chromosomal region, and autistic disorder associated with mental retardation, developmental problems and behavioral disorders. Combining classical and molecular ...
Cytogenetic analysis of a multinodular thyroid goiter
(1991-10-28)
Short-term cultures of a collagenase disaggregated multinodular goiter was shown by cytogenetic analysis to have the mosaic karyotype 47,XX,+7/48,XX,+7,+17/49,XX,+7,+10,+17. No cytogenetic data on goiter are available for ...