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Canonical WNT signaling regulates development of bovine embryos to the blastocyst stage
(2013-03-01)
Objectives were to evaluate the role of canonical WNT signaling in development of the preimplantation embryo. Signaling was activated with 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine (AMBMP) ...
WNT signaling in neuronal maturation and synaptogenesis
(Frontiers, 2013-07)
The Wnt signaling pathway plays a role in the development of the central nervous system and growing evidence indicates that Wnts also regulates the structure and function of the adult nervous system. Wnt components are key ...
Master regulators of epithelial-mesenchymal transition and wnt signaling pathways in juvenile nasopharyngeal angiofibromas
(2021-09-01)
Juvenile nasopharyngeal angiofibroma (JNA) is a rare fibrovascular benign tumor showing an invasive growth pattern and affecting mainly male adolescents. We investigated the role of epithelial–mesenchymal transition (EMT) ...
The Wnt signaling pathway and rheumatoid arthritis
(ELSEVIER SCIENCE BV, 2010)
The Wnt signaling pathways play a key role in cell renewal, and there are two such pathways. In patients with rheumatoid arthritis (RA), the synovial membrane expresses genes such as Wnt and Fz at higher levels than those ...
WNT16 is robustly increased by oncostatin m in mouse calvarial osteoblasts and acts as a negative feedback regulator of osteoclast formation induced by oncostatin M
(2021-01-01)
Background: Bone loss is often observed adjacent to inflammatory processes. The WNT signaling pathways have been implicated as novel regulators of both immune responses and bone metabolism. WNT16 is important for cortical ...
Consequences of endogenous and exogenous WNT signaling for development of the preimplantation bovine embryo
(2017-01-01)
The specific role of WNT signaling during preimplantation development remains unclear. Here, we evaluated consequences of activation and inhibition of ß-catenin (CTNNB1)-dependent and -independent WNT signaling in the ...
Non-canonical Wnt signalling and regulation of gastrulation movements
(Elsevier Ltd, 2002)
Members of the Wnt family have been implicated in a variety of developmental processes including axis formation, patterning of the central nervous system and tissue morphogenesis. Recent studies have shown that a Wnt ...
El receptor Ror1 y su rol en cancerThe role of Ror1 receptor in cancerO receptor Ror1 e seu papel em câncer
(Federación Bioquímica de la Provincia Buenos Aires, 2011-12)
Las proteínas Wnt son ligandos que activan señales involucradas en proliferación, sobrevida, adhesión, migración, diferenciación y polaridad celular y como tal están involucradas en una amplia variedad de patologías. A ...
CNBP modulates the transcription of Wnt signalling pathway components.
(Elsevier Science, 2014-08)
Background: Cellular nucleic acid binding protein (CNBP) is a small and highly conserved protein with nucleic acid chaperone activity that binds single-stranded nucleic acids. Data collected so far suggests that CNBP is ...