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Extracellular matrix stiffness and Wnt/β-catenin signaling in physiology and disease
(NLM (Medline), 2020)
Geoffroea decorticans fruit extracts inhibit the wnt/β-catenin pathway, a therapeutic target in cancer
(Academic Press Inc Elsevier Science, 2021-03)
Geoffroea decorticans (chañar) is commonly used for culinary and medicinal purposes in rural communities. The aim of this work was to chemically characterize three Geoffroea decorticans extracts and determine their capacity ...
WNT Signaling Is a Key Player in Alzheimer’s Disease
(Springer Science and Business Media Deutschland GmbH, 2021)
The cellular processes regulated by WNT signaling have been mainly studied during embryonic development and cancer. In the last two decades, the role of WNT in the adult central nervous system has been the focus of interest ...
Wnt3a ligand facilitates autophagy in hippocampal neurons by modulating a novel GSK-3β-AMPK axis
(2018)
Abstract
Background
In the adult central nervous system (CNS), Wnt signaling regulates dendritic structure and synaptic plasticity. The Wnt signaling pathway can be divided ...
β-catenin expression during the canine epidermal development
(Latin American Society for Developmental Biology, 2019)
β-catenin plays a central role both in the adherent intercellular junctions, as well as in the canonical Wnt signalling pathway. The study of the expression pattern of this protein during the canine epidermal development ...
Are changes in the wnt/b-catenin pathway involved in cocaine and stress-induced long-term neuroadaptations?
(Elyns Publishing group, 2017-10)
Drug addiction has been defined as a chronic relapsing brain disease, characterized by compulsive drug seeking and use, despite harmful consequences. This phenomenon has been extensively studied and the use of animal models ...
In vitro studies revealed a downregulation of Wnt/β-catenin cascade by active vitamin D and TX 527 analog in a Kaposi's sarcoma cellular model
(Pergamon-Elsevier Science Ltd, 2020-03)
The Kaposi´s sarcoma-associated herpesvirus G-protein-coupled receptor (vGPCR) is a key molecule in the pathogenesis of Kaposi´s sarcoma. We have previously demonstrated that 1α,25(OH)2D3 or its less calcemic analogTX 527 ...
Early stages of zebrafish eye formation require the coordinated activity of Wnt11, Fz5, and the Wnt/beta-catenin pathway
(CELL PRESS, 2005-07-07)
During regional patterning of the anterior neural plate, a medially positioned domain of cells is
specified to adopt retinal identity. These eye field cells remain coherent as they undergo
morphogenetic events distinct ...
WNT-β-catenin signaling pathway and its relationship with cancer [La vía de señalizacion Wnt-β-catenina y su relación con cancer]
(2012)
The Wnt-β-catenin signalling pathway plays a crucial role in the regulation, differentiation, proliferation and cellular death processes; consequently, alterations in this pathway are involved in nu-merous abnormalities ...
Hair follicle stem cell differentiation is inhibited through cross-talk between Wnt/β-catenin and androgen signalling in dermal papilla cells from patients with androgenetic alopecia
(Wiley Blackwell Publishing, Inc, 2012-05)
Background Hair follicle (HF) regeneration begins when signals from the mesenchyme-derived dermal papilla cells (DPC) reach multipotent epidermal stem cells in the bulge region. Wnt/β-catenin signalling is known to affect ...