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Histo‐morphology of the thyroid gland during the larval development of Pleurodema borellii (Anura, Leptodactylidae)
(Wiley Blackwell Publishing, Inc, 2020-10-11)
The thyroid gland is essential in anurans, since thyroid hormones (TH) are the main regulators of larval development. Its absence or inactivity interrupts development and precludes metamorphosis. Histological changes are ...
Histology and microscopic anatomy of the thyroid gland during the larval development of Pseudis platensis (Anura, Hylidae)
(Veterinary and Human Toxicology, 2019-11-08)
Several hormones regulate anuran larval development, most notably thyroid hormones (THs). In anurans, metamorphosis fails when the thyroid gland is absent or inactivated, resulting in giant tadpoles. Larval gigantism occurs ...
Hexachlorobenzene triggers apoptosis in rat thyroid follicular cells
(Oxford University Press, 2009-04)
Hexachlorobenzene (HCB) is a widespread environmental pollutant. Chronic exposure of humans to HCB produces a number of effects, such as triggering of porphyria, increased synthesis of liver microsomal enzymes, neurological ...
Differences in responsiveness and sensitivity to exogenous disruptors of the thyroid gland in three anuran species
(Wiley-liss, div John Wiley & Sons Inc., 2019-11)
Anuran larval development comprises tissues/organs/systems that are: exclusively of larvae, able to be remodelled, and those of postmetamorphic stages. Also, the anuran larval development is characterized by inter-related ...
The role of thyroglobulin in thyroid hormonogenesis
(Springer, 2019-06)
In humans, the thyroid hormones T3 and T4 are synthesized in the thyroid gland in a process that crucially involves the iodoglycoprotein thyroglobulin. The overall structure of thyroglobulin is conserved in all vertebrates. ...
Pituitary–thyroid axis development during the larval–juvenile transition in the pejerrey Odontesthes bonariensis
(Wiley Blackwell Publishing, Inc, 2017-09)
The morphological development of the thyroid gland of pejerrey Odontesthes bonariensis during larval–juvenile transition was studied and related to whole-body concentrations of thyroxine (T4) and tri-iodothyronine (T3). A ...
NFE2-Related transcription factor 2 coordinates antioxidant defense with thyroglobulin production and iodination in the thyroid gland
(Mary Ann Liebert, 2018-06)
Background: The thyroid gland has a special relationship with oxidative stress. While generation of oxidative substances is part of normal iodide metabolism during thyroid hormone synthesis, the gland must also defend ...
The expression of estrogen, prolactin, and progesterone receptors in mammary gland and liver of female rats during pregnancy and early postpartum: Regulation by thyroid hormones
(Taylor & Francis, 2005-12)
The aim of this study was to examine, using semiquantitative reverse transcriptase-polymerase chain reaction (RT-PCR) the changes in mRNA expression of the two estrogen receptor (ER) subtypes, ERα and ERβ, prolactin receptor ...
Long-term effects of in ovo exposure to an environmentally relevant dose of atrazine on the thyroid gland of Caiman latirostris
(Academic Press Inc Elsevier Science, 2020-07)
The increased incidence of human thyroid disorders, particularly in women, suggests that the exposure to endocrine-disrupting compounds (EDCs) together with sex-related factors could play a role in thyroid dysregulation. ...
Thyroid hormones and heart mitochondrial nitric oxide under hypovolemia
(MedCrove, 2018-09)
The aim of the present work was to examine the effect of thyroid state on rat heart mitochondria function during hypovolemia. Sprague-Dawley rats treated with T3 (hyper, 20 μg/100 g body weight) or 0.02% methimazole (hypo, ...