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Data of ureagenesis from ammonia, glutamine and alanine, and mitochondrial aquaporin-8 expression in thioacetamide-treated hepatocytes
(Elsevier, 2020-06)
We present data about the synthesis of urea from different substrates, i.e., free ammonia, glutamine and alanine in primary cultured rat hepatocytes treated or untreated with the model hepatotoxic agent thioacetamide (TAA). ...
Microwave-assisted conditions for the green synthesis of thioacetamide. Optimization of reaction parameters using response surface methodology
(Elsevier B.V., 2018-09)
An optimized method for the synthesis of thioacetamide (TA) in relation to the consumption of materials and energy, which reduces the production of waste and minimizes costs, is hitherto presented. The most important ...
SPARC gene deletion protects against toxic liver injury and is associated to an enhanced proliferative capacity and reduced oxidative stress response
(Impact Journals, 2016-05)
SPARC, also known as osteonectin and BM-40, is a matricellular protein with a number of biological functions. Hepatic SPARC expression is induced in response to thioacetamide, bile-duct ligation, and acute injuries such ...
Anodic sulphuration of submicron-grained thin films for ir sensing
(Asociación Química Argentina, 2005-12)
Equilibrium and kinetic properties of the anodic sulphuration of magnetron sputtered lead thin films at room temperature are reviewed. Tafel plots and cyclic voltametry data demonstrate the existence of competing two ...
One-pot synthesis, quantum chemical calculations and X-ray diffraction studies of thiazolyl-coumarin hybrid compounds
(Pergamon-Elsevier Science Ltd, 2018-06)
Two closely related hybrid species containing both, thiazolyl and coumarin groups, were synthesized by using two different one-pot procedures from a common precursor. The reaction of α-bromoacetylcoumarin with thioacetamide ...
Human umbilical cord perivascular cells-derived extracellular vesicles mediate the transfer of IGF-I to the liver and ameliorate hepatic fibrogenesis in mice
(Nature Publishing Group, 2019-09)
Extracellular vesicles (EVs) can mediate mesenchymal stromal cells (MSCs) paracrine effects. We aimed to evaluate the therapeutic potential of human umbilical cord perivascular cells (HUCPVCs) engineered to produce Insulin ...
4-Methylumbelliferone inhibits hepatocellular carcinoma growth by decreasing IL-6 production and angiogenesis
(Oxford University Press, 2015-08)
Cirrhosis is characterized by an excessive accumulation of extracellular matrix components including hyaluronic acid (HA) and is widely considered a pre-neoplastic condition for hepatocellular carcinoma (HCC). 4-methylum ...