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Non-genomic actions of estradiol and 4-OH-tamoxifen on murine breast cancer cells
(Spandidos Publications, 2015-01)
Estrogens and tamoxifen do not only exert their effects at the genomic level, but also play a role at the cell membrane activating downstream signaling pathways. We recently characterized an estrogen receptor-positive ...
Assessment of Vascular Effects of Tamoxifen and Its Metabolites on the Rat Perfused Hindquarter Vascular Bed
(WILEY-BLACKWELL PUBLISHING, INC, 2009)
Tamoxifen has been suggested to produce beneficial cardiovascular effects, although the mechanisms for these effects are not fully known. Moreover, although tamoxifen metabolites may exhibit 30-100 times higher potency ...
Adsorptive potentiometric stripping analysis of trace tamoxifen at a glassy carbon electrode
(Elsevier B.V., 1997-12-19)
A highly sensitive adsorptive stripping procedure for trace measurement of the anticancer drug tamoxifen is described. The method is based on controlled adsorptive accumulation of the drug at an electrochemically treated ...
Endometrial polyp with sex cord-like pattern
(Lippincott Williams & WilkinsPhiladelphiaEUA, 2006)
Oral stomatitis induced by endogenous progesterone: Case report
(2009-11-09)
Oral stomatitis induced by endogenous progesterone is a rare clinical condition which may be associated with cutaneous involvement. That is probably due to the peak of progesterone production during the luteal phase of the ...
Tamoxifen as a potential antileishmanial agent: efficacy in the treatment of Leishmania braziliensis and Leishmania chagasi infections
(OXFORD UNIV PRESS, 2009)
The aim of this study was to evaluate the efficacy of tamoxifen in vivo in experimental models of cutaneous (CL) and visceral leishmaniasis (VL) caused by Leishmania braziliensis and Leishmania chagasi, respectively. Drug ...
Tamoxifen selects for breast cancer cells with mammosphere forming capacity and increased growth rate.
(Springer, 2013-12)
Using the M05 mouse mammary tumor model and the MCF-7 cell line, we investigated the effect of tamoxifen treatment on the fraction of breast cancer cells with self-renewing capacity both in vitro and in vivo. We found that ...