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Screening of transcription factors involved in fetal hemoglobin regulation using phylogenetic footprinting
(2015-10-27)
Fetal hemoglobin (Hb F) is an important genetic modulator of the beta-hemoglobinopathies. The regulation of Hb F levels is influenced by transcription factors. We used phylogenetic footprinting to screen transcription ...
Immunomodulatory effect of vitamin D on the STATs and transcription factors of CD4+ T cell subsets in pregnant women with preeclampsia
(2022-01-01)
This study evaluated the in vitro modulatory effect of vitamin D (VD) on T cells, by determining the expression of STATs and the transcription factors of each CD4+ T cell subsets. Twenty women with preeclampsia (PE) and ...
Molecular characterization of ScTFIIA gamma, encoding the putative TFIIA small subunit from sugarcane
(SpringerNew YorkEUA, 2010)
A Genome-wide Screen for Neurospora crassa Transcription Factors Regulating Glycogen Metabolism
(Amer Soc Biochemistry Molecular Biology Inc, 2011-11-01)
Transcription factors play a key role in transcription regulation as they recognize and directly bind to defined sites in promoter regions of target genes, and thus modulate differential expression. The overall process is ...
Multiple mechanisms of growth hormone-regulated gene transcription
(Elsevier, 2007)
Diverse physiological actions of growth hormone (GH) are mediated by changes in gene transcription. Transcription can be regulated at several levels, including post-translational modification of transcription factors, and ...
Abscisic acid (ABA) and low temperatures synergistically increase the expression of CBF/DREB1 transcription factors and cold-hardiness in grapevine dormant buds
(Oxford University Press, 2019)
Background and Aims: It has been reported that low temperatures (LTs) and the plant hormone abscisic acid (ABA) induce the expression of CBF/DREB1 transcription factors in vegetative tissues and seedlings of Vitis vinifera ...
Non-coding transcript in T cells (NTT): Antisense transcript activates PKR and NF-kappa B in human lymphocytes
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2008)
T cell activation is a complex process involving many steps and the role played by the non-protein-coding RNAs (ncRNAs) in this phenomenon is still unclear. The non-coding T cells transcript (NTT) is differentially expressed ...
MicroRNA-mRNA Co-sequencing Identifies Transcriptional and Post-transcriptional Regulatory Networks Underlying Muscle Wasting in Cancer Cachexia
(Frontiers Media Sa, 2020-05-29)
Cancer cachexia is a metabolic syndrome with alterations in gene regulatory networks that consequently lead to skeletal muscle wasting. Integrating microRNAs-mRNAs omics profiles offers an opportunity to understand ...
Expression of transcription factors NF-kappa B and AP-1 in nasal polyposis
(BLACKWELL PUBLISHING, 2008)
Background The treatment and prognosis of nasal polyposis (NP) may be influenced by transcription factors, but their expression is poorly understood. Objective To determine the expression of transcription factors [(nuclear ...