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Expression of TLR2 and TLR4 in lesions of patients with tegumentary american leishmaniasisExpressão de TLR2 e TLR4 em lesões de pacientes com leishmaniose tegumentar americana
(Instituto de Medicina Tropical, 2012)
OBJECTIVES: The aim of this study was to describe the pattern of expression of Toll-like receptor 2 (TLR2) and Toll-like receptor 4 (TLR4) in skin biopsies of patients with American tegumentary leishmaniasis (ATL) caused ...
Expression of TLR-4 and -2 in peripheral mononuclear cells in renal transplant patients with TLR-4 gene polymorphism
(ELSEVIER SCIENCE BV, 2010)
Introduction: TLR-4 has also been identified as a receptor for endogenous alarmins, which are increased post transplantation. TLR-4 has also been associated with a polymorphism that could impact graft outcome. Objective: ...
Expression of toll-like receptor-2 and -4 in amniochorion membranes of preterm delivery in the presence of histologic chorioamnionitis
(2014)
Expression of Toll-like receptors at the maternal-fetal interface during normal and complicated pregnancies has aroused interest in the last few years. However, despite the importance of TLR-2 and TLR-4, which recognizes ...
Effect of helicobacter pylori eradication on TLR2 and TLR4 expression in patients with Gastric Lesions
(Hindawi Publishing Corporation, 2015-01-01)
Objective. Helicobacter pylori (Hp) is recognized by TLR4 and TLR2 receptors, which trigger the activation of genes involved in the host immune response. Thus, we evaluated the effect of eradication therapy on TLR2 and ...
Propolis immunomodulatory activity on TLR-2 and TLR-4 expression by chronically stressed mice
(Taylor & Francis Ltd, 2012-01-01)
Our group has been investigating the immunomodulatory activity of propolis in stressed mice. In this work, we wish to report the action of propolis in chronically stressed mice, assessing the Toll-like receptor (TLR2 and ...
The involvement of TLR2 and TLR4 in cytokine and nitric oxide production in visceral leishmaniasis patients before and after treatment with anti-leishmanial drugs
(Public Library Science, 2015-02-23)
Toll-like receptors (TLRs) have significant involvement in Leishmania infection, although little is known about the relationship between these receptors, cytokines and nitric oxide (NO) in patients with visceral leishmaniasis ...
Role of TLR2 and TLR4 in Human Neutrophil Functions Against Paracoccidioides brasiliensis
(Wiley-Blackwell Publishing, Inc, 2010-02-01)
In paracoccidioidomycosis, a systemic mycosis caused by the fungus Paracoccidioides brasiliensis (Pb), studies have focused on the role of neutrophils that are involved in primary response to the fungus. Neutrophil functions ...
Influence of TLR-2 in the immune response in the infection induced by fungus Sporothrix schenckii
(2014-01-01)
Toll-like receptors (TLRs) play an important role in immunity, since they bind to pathogen surface antigens and initiate the immune response. However, little is known about the role of TLR-2 in the recognition of S. schenckii ...
TLR2- and 4-independent immunomodulatory effect of high molecular weight components from Ascaris suum
(Pergamon PressOxford, 2014-03)
Components of high molecular-weight (PI) obtained from Ascaris suum extract down-regulate the Th1/Th2-related immune responses induced by ovalbumin (OVA)-immunization in mice. Furthermore, the PI down-modulates the ability ...
P-MAPA immunotherapy potentiates the effect of cisplatin on serous ovarian carcinoma through targeting TLR4 signaling
(2018-01-17)
Background: Toll-like receptors (TLRs) are transmembrane proteins expressed on the surface of ovarian cancer (OC) and immune cells. Identifying the specific roles of the TLR-mediated signaling pathways in OC cells is ...