Now showing items 1-10 of 269
Alternative splicing and transcription elongation in plants
(Frontiers Media S.A., 2019-03)
Alternative splicing and transcription elongation by RNA polymerase II (RNAPII) are two processes which are tightly connected. Splicing is a co-transcriptional process, and different experimental approaches show that ...
Global transcriptome analysis reveals circadian control of splicing events in Arabidopsis thaliana
(Wiley Blackwell Publishing, Inc, 2020-05)
The circadian clock of Arabidopsis thaliana controls many physiological and molecular processes, allowing plants to anticipate daily changes in their environment. However, developing a detailed understanding of how ...
Splicing regulation by long noncoding RNAs
(Oxford University Press, 2018-02)
Massive high-throughput sequencing techniques allowed the identification of thousands of noncoding RNAs (ncRNAs) and a plethora of different mRNA processing events occurring in higher organisms. Long ncRNAs can act directly ...
Long range chromatin organization: a new layer in splicing regulation?
(Landes Bioscience, 2014-04)
Splicing is a predominantly co-transcriptional process that has been shown to be tightly coupled to transcription. Chromatin structure is a key factor that mediates this functional coupling. In light of recent evidence ...
Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition
(Nature Research, 2021-12)
Alternative splicing relies on the combinatorial recruitment of splicing regulators to specific RNA binding sites. Chromatin has been shown to impact this recruitment. However, a limited number of histone marks have been ...
Alternative splicing switches: Important players in cell differentiation
(John Wiley & Sons Inc, 2017-06-27)
Alternative splicing (AS) greatly expands the coding capacities of genomes by allowing the generation of multiple mature mRNAs from a limited number of genes. Although the massive switch in AS profiles that often accompanies ...
Characterization of Three cDNAs obtained by spliced Leader-PCR screening of a Taenia solium cDNA library
(Universidad Nacional, Costa Rica, 2022)
The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators
(Oxford University Press, 2016-10-17)
Alternative splicing (AS) is a key component of gene expression programs that drive cellular differentiation. Smooth muscle cells (SMCs) are important in the function of a number of physiological systems; however, investigation ...
Epigenetics in Alternative Pre-mRNA Splicing
(Cell Press, 2011-01)
Alternative splicing plays critical roles in differentiation, development, and disease and is a major source for protein diversity in higher eukaryotes. Analysis of alternative splicing regulation has traditionally focused ...
Chromatin, DNA structure and alternative splicing
(Elsevier Science, 2015-06)
Coupling of transcription and alternative splicing via regulation of the transcriptional elongation rate is a well-studied phenomenon. Template features that act as roadblocks for the progression of RNA polymerase II ...