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Sensitivity and specificity of the ICDAS II system and bitewing radiographs for detecting occlusal caries using the Spectra™ caries detection system as the reference test in children
(BioMed Central, 2023)
Background: Most studies assessing the sensitivity and specificity of caries detection methods have been performed in vitro using the histological method as the gold standard showing inconsistent values. The aim of this ...
Analytical sensitivity of current best-in-class malaria rapid diagnostic tests
(BioMed Central, 2017)
BACKGROUND: Rapid diagnostic tests (RDTs) are today the most widely used method for malaria diagnosis and are recommended, alongside microscopy, for the confirmation of suspected cases before the administration of anti-malarial ...
A pangenome approach-based loop-mediated isothermal amplification assay for the specific and early detection of Bordetella pertussis
(Nature Research, 2023)
Despite widespread vaccination, Bordetella pertussis continues to cause pertussis infections worldwide, leaving infants at the highest risk of severe illness and death, while people around them are likely the main sources ...
A new approach for pyrazinamide susceptibility testing in mycobacterium tuberculosis
(Mary Ann Liebert, 2012)
Background: Pyrazinamide (PZA) is an important drug in the treatment of tuberculosis. Microbiological methods of PZA susceptibility testing are controversial and have low reproducibility. After conversion of PZA into ...
Sensitivity and specificity of three diabetes diagnostic criteria in people with non-alcoholic fatty liver disease (NAFLD) and otherwise healthy people: Analysis of NHANES III.
(Elsevier, 2023)
AIMS: Establishing whether fasting plasma glucose (FPG), postprandial glucose (PPG), and HbA1c have the same diagnostic accuracy in NAFLD versus otherwise healthy people could inform T2DM screening recommendations for ...
Feasibility of the TBDx automated digital microscopy system for the diagnosis of pulmonary tuberculosis
(Public Library of Science, 2017)
BACKGROUND: Improved and affordable diagnostic or triage tests are urgently needed at the microscopy centre level. Automated digital microscopy has the potential to overcome issues related to conventional microscopy, ...
Laboratory Evaluation of a Dual-Path Platform Assay for Rapid Point-of-Care HIV and Syphilis Testing
(American Society for Microbiology, 2016)
We assessed the laboratory performance of the Chembio dual-path platform HIV-syphilis rapid immunodiagnostic test and electronic reader for detection of HIV and Treponema pallidum antibodies in 450 previously characterized ...
Diagnostic accuracy among 4 point-of-care tests for the screening of HIV infection
(Oxford University Press, 2013)
The aim of this study was to validate and compare 4 point-of-care (POC) devices for the detection of antibodies to human immunodeficiency virus 1 (HIV-1) and/or HIV-2 in cryopreserved serum specimens. We analyzed 99 specimens ...
Kato-Katz and Lumbreras rapid sedimentation test to evaluate helminth prevalence in the setting of a school-based deworming program
(Taylor and Francis, 2016)
The sensitivity of the Kato-Katz test is suboptimal for the evaluation of intestinal helminth prevalence. Moreover, during mass deworming, as helminth egg burden decreases, the sensitivity is likely to decrease. The ...
Morphological characterization of Mycobacterium tuberculosis in a MODS culture for an automatic diagnostics through pattern recognition
(Public Library of Science, 2013)
Tuberculosis control efforts are hampered by a mismatch in diagnostic technology: modern optimal diagnostic tests are least available in poor areas where they are needed most. Lack of adequate early diagnostics and MDR ...