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Adaptive threshold in TiO 2 -based synapses
(IOP Publishing, 2019-01)
We measured and analyzed the dynamic and remnant current-voltages curves of Al/TiO2/Au and Ni/TiO2/Ni/Au memory devices in order to understand the conduction mechanisms and their synapse-like memory properties. Current ...
Postsynaptic recordings at afferent dendrites contacting cochlear inner hair cells: Monitoring multivesicular release at a ribbon synapse
(Journal of Visualized Experiments, 2011-02)
The afferent synapse between the inner hair cell (IHC) and the auditory nerve fiber provides an electrophysiologically accessible site for recording the postsynaptic activity of a single ribbon synapse. Ribbon synapses of ...
Cochlear hair cells: The sound-sensing machines
(Elsevier, 2015-08-31)
The sensory epithelium of the mammalian inner ear contains two types of mechanosensory cells:inner (IHC) and outer hair cells (OHC). They both transduce mechanical force generated by soundwaves into electrical signals. In ...
Lithium causes differential effects on postsynaptic stability in normal and denervated neuromuscular synapses
(Nature Research, 2021-12)
Lithium chloride has been widely used as a therapeutic mood stabilizer. Although cumulative evidence suggests that lithium plays modulatory effects on postsynaptic receptors, the underlying mechanism by which lithium ...
Early activation of CD95 is limited and localized to the cytotoxic synapse
(Wiley Blackwell Publishing, Inc, 2018-08)
The cytotoxic synapse formed between cytotoxic T lymphocytes or natural killer cells expressing CD95L and target cells with CD95 on their surface is a key pathway for apoptosis induction by the immune system. Despite ...
Transition to synchronization in heterogeneous inhibitory neural networks with structured synapses
(American Institute of Physics, 2021-03)
Inhibitory neurons form an extensive network involved in the development of different rhythms in the cerebral cortex. A transition from an incoherent state, where all inhibitory neurons fire unrelated to each other, to a ...
Activity of nAChRs containing α9 subunits modulates synapse stabilization via bidirectional signaling programs
(John Wiley & Sons Inc, 2009-12)
Although the synaptogenic program for cholinergic synapses of the neuromuscular junction is well known, little is known of the identity or dynamic expression patterns of proteins involved in non-neuromuscular nicotinic ...
Early changes in the synapses of the neostriatum induced by perinatal asphyxia
(Taylor & Francis, 2012-05)
Perinatal asphyxia (PA) is a medical condition associated with a high short-term morbimortality and different long-term neurological diseases. In previous work we have observed at 6 months post-synaptic densities (PSDs) ...
Cc2d1a, a C2 domain containing protein linked to nonsyndromic mental retardation, controls functional maturation of central synapses
(American Physiological Society, 2011-04)
Cc2d1a is an evolutionarily conserved protein composed of NH2-terminal Drosophila melanogaster 14 domain (DM14) domains and a COOH-terminal C2 domain. Human patients with homozygotic mutation in the gene suffer from ...