Buscar
Mostrando ítems 1-10 de 125
CaMKIId Splice variants in the healthy and diseased heart
(Frontiers Media, 2021)
RNA splicing has been recognized in recent years as a pivotal player in heart
development and disease. The Ca2C/calmodulin dependent protein kinase II delta
(CaMKIId) is a multifunctional Ser/Thr kinase family and generates ...
Differential expression of new LTA splice variants upon lymphocyte activation
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
Lymphotoxin alpha (LTA) is a member of the TNF cytokine superfamily, produced principally by lymphocytes. It plays an important role in immune and inflammatory responses. Many TNF superfamily members have functionally ...
The connection between splicing and cancer
(Company Of Biologists, 2006)
Alternative splicing is a crucial mechanism for generating protein diversity. Different splice variants of a given protein can display different and even antagonistic biological functions. Therefore, appropriate control ...
A new portal for the analysis of human splicing variants
(LANDES BIOSCIENCEAUSTIN, 2012)
Understanding alternative splicing is crucial to elucidate the mechanisms behind several biological phenomena, including diseases. The huge amount of expressed sequences available nowadays represents an opportunity and a ...
Venomics of the Australian eastern brown snake (Pseudonaja textilis): detection of new venom proteins and splicing variants
(Elsevier B. V., 2015)
The eastern brown snake is the predominant cause of snakebites in mainland Australia. Its venom induces defibrination coagulopathy, renal failure and microangiopathic hemolytic anemia. Cardiovascular collapse has been ...
Heteroduplex formation and S1 digestion for mapping alternative splicing sites
(FUNPEC-EDITORA, 2008)
The identification of alternatively spliced transcripts has contributed to a better comprehension of developmental mechanisms, tissue-specific physiological processes and human diseases. Polymerase chain reaction amplification ...
In silico structural and functional characterization of the RSUME splice variants Short title: RSUME splice variants
(Public Library Science, 2013-02)
RSUME (RWD-containing SUMO Enhancer) is a small protein that increases SUMO conjugation to proteins. To date, four splice variants that codify three RSUME isoforms have been described, which differ in their C-terminal end. ...
Functional Characterization of NIPBL Physiological Splice Variants and Eight Splicing Mutations in Patients with Cornelia de Lange Syndrome
(Molecular Diversity Preservation International, 2014-05)
Cornelia de Lange syndrome (CdLS) is a congenital developmental disorder characterized by distinctive craniofacial features, growth retardation, cognitive impairment, limb defects, hirsutism, and multisystem involvement. ...
Expression of LH receptor mRNA splice variants in bovine granulosa cells: Changes with follicle size and regulation by FSH in vitro
(Wiley-Blackwell, 2007-06-01)
In cattle, most evidence suggests that granulosa cells express LH receptors (LHR) after (or as) the follicle becomes dominant, however there is some suggestion that granulosa cells from smaller pre-dominant follicles may ...
Characterisation of a new splice variant of MASK-BP3(ARF) and MASK human genes, and their expression patterns during haematopoietic cell differentiation
(Elsevier Science BvAmsterdamHolanda, 2005)