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Purification of n-boc-Rolipram racemate on chiral stationary phase using simulated moving bed chromatography under linear conditions

Goncalves, CV; Carpes, MJS; Correia, CRD; Santana, CC (Elsevier Science SaLausanneSuíça, 2008)

Determination of the kinetic and equilibrium parameters of the n-boc-rolipram enantiomers on a chiral stationary phase by high performance liquid chromatography

Goncalves, CV; Carpes, MJS; Correa, CRD; Santana, CC (Elsevier Science SaLausanneSuíça, 2007)

Synthesis of 4-aryl-2-pyrrolidones and beta-aryl-gamma-amino-butyric acid (GABA) analogues by heck arylation of 3-pyrrolines with arenediazonium tetrafluoroborates. Synthesis of (+/-)-rolipram on a multigram scale and chromatographic resolution by semipreparative chiral simulated moving bed chromatography

Garcia, ALL; Carpes, MJS; de Oca, ACBM; dos Santos, MAG; Santana, CC; Correia, CRD (Amer Chemical SocWashingtonEUA, 2005)

Synthesis Of 4-aryl-2-pyrrolidones And Beta-aryl-gamma-amino-butyric Acid (gaba) Analogues By Heck Arylation Of 3-pyrrolines With Arenediazonium Tetrafluoroborates. Synthesis Of (+/-)-rolipram On A Multigram Scale And Chromatographic Resolution By Semipreparative Chiral Simulated Moving Bed Chromatography.

Garcia, Ariel L L; Carpes, Marcos J S; de Oca, Antonio C B M; dos Santos, Marco A G; Santana, César C; Correia, Carlos Roque D (2005)

High-performance Liquid Chromatographic Separation Of Rolipram, Bupivacaine And Omeprazole Using A Tartardiamide-based Stationary Phase Influence Of Flow Rate And Temperature On The Enantioseparation.

da Silva Junior, Ivanildo José; Sartor, João Paulo; Rosa, Paulo César Pires; de Veredas, Vinícius; Barreto Júnior, Amaro Gomes; Santana, Cesar Costapinto (2007)

Phosphodiesterase 4 inhibition restrains muscle proteolysis in diabetic rats by activating PKA and EPAC/Akt effectors and inhibiting FoxO factors

Universidade Estadual Paulista (Unesp); Universidade de São Paulo (USP); Federal University of Ouro Preto (2021-08-01)

Aim: There is growing evidence about the ability of cyclic adenosine monophosphate (cAMP) signaling and nonselective phosphodiesterase (PDE) inhibitors on mitigate muscle atrophy. PDE4 accounts for the major cAMP hydrolyzing ...

Ação do inibidor de fosfodiesterase 4 rolipram na músculatura lisa das vias aéreas: interferência na via extracelular AMPc- Adenosina

Freitas, Bianca (2022)

Separação do racemato N-Boc-Rolipram pelo processo cromatografico de leito movel simulado utilizando fase estacionaria quiral tris-(3,5-dimetilfenilcarbamato de celulose) suportada em silica

Gonçalves, Caroline Vieira ([s.n.], 2005)

Inibidores de fosfodiesterases e o controle de processos proteolíticos na atrofia muscular induzida pelo diabetes mellitus

Baviera, Amanda Martins [UNESP]; Universidade Estadual Paulista (Unesp) (Universidade Estadual Paulista (Unesp), 2018-04-27)

Considerando os avanços no conhecimento acerca dos mecanismos que controlam o metabolismo de proteínas na musculatura esquelética que permitiram a busca por novas opções para o tratamento das atrofias musculares, o presente ...

TcPDE4, a novel membrane-associated cAMP-specific phosphodiesterase from Trypanosoma cruzi

Alonso, Guillermo Daniel; Schoijet, Alejandra Cecilia; Torres, Hector Norberto; Flawia, Mirtha Maria (Elsevier Science, 2006-01)

Cyclic nucleotide phosphodiesterases constitute the only known mechanism to inactivate regulatory signals involving cAMP or cGMP. In our laboratory a cAMP-specific phosphodiesterase associated to the flagellar apparatus, ...

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