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Melatonin as a therapeutic tool in ophtalmology : implication for glaucoma and uveitis
(2010)
Abstract: Several lines of evidence support the view that increased free radical generation and altered nitric oxide (NO) metabolism play a role in the pathogenesis of highly prevalent ocular diseases, such as glaucoma and ...
Melatonin in mitochondrial dysfunction and related disorders
(Hindawi, 2011)
Abstract: Mitochondrial dysfunction is considered one of the major causative factors in the aging process, ischemia/reperfusion (I/R), septic shock, and neurodegenerative disorders like Parkinson’s disease (PD), Alzheimer’s ...
Potential use of melatonergic drugs in analgesia : mechanisms of action
(Elsevier, 2010)
abstract: Melatonin is a remarkable molecule with diverse physiological functions. Some of its effects are mediated by receptors while other, like cytoprotection, seem to depend on direct and indirect scavenging of free ...
Chronophysiology of melatonin : therapeutical implications
(2010)
Abstract: Normal circadian rhythms are synchronized to a regular 24 hr environmental light/dark cycle. Both the suprachiasmatic nucleus (SCN) and melatonin are essential for this adaptation. Melatonin exerts its ...
Melatonina y consumo de benzodiacepinas : un ejemplo de medicina traslacional
(Ediciones Médicas del Sur, 2015)
Resumen: El abuso en el consumo de benzodiacepinas (BZP) y drogas Z se ha transformado, debido a la tolerancia y dependencia que producen, en un grave problema de salud pública. Treinta años atrás demostramos en animales ...
Melatonin receptors (version 2019.4) in the IUPHAR/BPS Guide to pharmacology database
(University of Edinburgh, 2019)
Melatonin receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Melatonin Receptors [36]) are activated by the endogenous ligands melatonin and clinically used drugs like ramelteon, agomelatine and tasimelteon
Melatonin in chagas disease : possible therapeutic value
(Fundación Revista Medicina, 2011)
Abstract: Chagas’ disease is a severe health problem in Latin America, causing approximately 50 000 deaths a year, with approximately 18 million infected people. About 25-30% of the patients infected with Trypanosoma cruzi ...
Agomelatine : its role in the management of major depressive disorder
(Libertas Academica, 2012)
Abstract: Circadian rhythm abnormalities, as shown by sleep/wake cycle disturbances, constitute one the most prevalent signs of depressive illness; advances or delays in the circadian phase are documented in patients with ...
Malaria : therapeutic implications of melatonin
(Wiley, 2010)
Abstract: Malaria, which infects more than 300 million people annually, is a serious disease. Epidemiological surveys indicate that of those who are affected, malaria will claim the lives of more than one million individuals, ...
Melatonin and its analogs in insomnia and depression
(2012)
Abstract: Benzodiazepine sedative hypnotic drugs are widely used for treatment of insomnia. Nevertheless, their adverse effects, such as next-day hangover, dependence and impairment of memory, make them unsuitable for long ...