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Receptor for advanced glycation end-products axis and coronavirus disease 2019 in inflammatory bowel diseases: A dangerous liaison?
(Baishideng Publishing Group, 2021)
Compelling evidence supports the crucial role of the receptor for advanced
glycation end-products (RAGE) axis activation in many clinical entities. Since the
beginning of the coronavirus disease 2019 pandemic, there is ...
Inhibition of RAGE axis signaling: A pharmacological challenge
(Bentham Science Publishers B.V., 2019)
The Receptor for Advanced Glycation End Products (RAGE) is an important cell surface receptor, which belongs to the IgG super family and is now considered as a pattern recognition receptor. Because of its relevance in many ...
Advanced glycation and ROS: A link between diabetes and heart failure
(2008)
Despite many advances achieved to date, heart failure (HF) remains a leading cause of morbidity and mortality. There is a widely-accepted consensus that HF and diabetes are strongly linked by at least 3 mechanisms: associated ...
Polyphenols and AGEs/RAGE axis. Trends and challenges
(Elsevier, 2020)
The formation of advanced glycation end-products (AGEs) is a key pathophysiological event linked not only to the onset and progression of diabetic complications, but also to neurodegeneration, cardiovascular diseases, ...
SARS-CoV-2-mediated inflammatory response in lungs: should we look at RAGE?
(Springer, 2020)
The novel coronavirus disease (COVID-19) pandemic is placing significant strains on health systems, scientific communities, essential public services, and economies all over the world. In this context, the world ' s ...
Dietary Advanced Glycation End Products and Their Role in Health and Disease
(American Society for Nutrition, 2015)
Over the past 2 decades there has been increasing evidence supporting an important
contribution from food-derived advanced glycation end products (AGEs) to the body pool of
AGEs and therefore increased oxidative stress ...
Systemic Inflammation Changes the Site of RAGE Expression from Endothelial Cells to Neurons in Different Brain Areas
(Molecular Neurobiology, 2018)
The damage signals hypothesis of Alzheimer's disease pathogenesis
(IOS Press, 2008)
Virtually none of the hypotheses on Alzheimer's disease (AD) pathogenesis address the earliest events that trigger the molecular alterations that precede cerebral degeneration and account for the diversity of risk factors ...
HGMB1 and RAGE as essential components of Ti osseointegration process in mice
(Frontiers Media, 2019)
The release of the prototypic DAMP High Mobility Group Box 1 (HMGB1) into extracellular environment and its binding to the Receptor for Advanced Glycation End Products (RAGE) has been described to trigger sterile inflammation ...