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The Notch system during pubertal development of the bovine mammary gland
(Nature Publishing Group, 2019-06)
The development of the mammary gland of cows during pre-weaning and puberty will condition its future productive capacity and warrants special study. In this respect, Notch signaling regulates tissue development and fate ...
TGF‐β pro‐oligodendrogenic effects on adult SVZ progenitor cultures and its interaction with the Notch signaling pathway
(Wiley-liss, Div John Wiley & Sons Inc, 2018-02)
Adult neural progenitor cells (NPCs) are capable of differentiating into neurons, astrocytes, and oligodendrocytes throughout life. Notch and transforming growth factor b1 (TGF-b) signaling pathways play critical roles in ...
Role of BMP signaling and the homeoprotein iroquois in the specification of the cranial placodal field
(Academic Press Inc Elsevier Science, 2004-08)
Different types of placodes originate at the anterior border of the neural plate but it is still an unresolved question whether individual placodes arise as distinct ectodermal specializations in situ or whether all or a ...
Transcriptome Modifications in Porcine Adipocytes via Toll-Like Receptors Activation
(Frontiers Media S.A., 2019-05)
Adipocytes are the most important cell type in adipose tissue playing key roles in immunometabolism. We previously reported that nine members of the Toll-like receptor (TLR) family are expressed in an originally established ...
Cancer stem cells: Culprits in endocrine resistance and racial disparities in breast cancer outcomes
(Elsevier Ireland, 2021-03)
Breast cancer stem cells (BCSCs) promote endocrine therapy (ET) resistance, also known as endocrine resistance in hormone receptor (HR) positive breast cancer. Endocrine resistance occurs via mechanisms that are not yet ...
Changes in the expression of genes involved in the ovarian function of rats caused by daily exposure to 3-methylcholanthrene and their prevention by α-naphthoflavone
(Springer, 2017-11)
Daily exposure to low doses of 3-methylcholanthrene (3MC) during the pubertal period in rats disrupts both follicular growth and ovulation. Thus, to provide new insights into the toxicity mechanism of 3MC in the ovary, ...
The testicular transcriptome associated with spermatogonia differentiation initiated by gonadotrophin stimulation in the juvenile rhesus monkey (Macaca mulatta)
(Oxford University Press, 2017-10)
STUDY QUESTION What is the genetic landscape within the testis of the juvenile rhesus monkey (Macaca mulatta) that underlies the decision of undifferentiated spermatogonia to commit to a pathway of differentiation when ...
A cladistic revision of Tortopus Needham & Murphy with description of the new genus Tortopsis (Ephemeroptera: Polymitarcyidae)
(Magnolia Press, 2010-05)
Se realiza un análisis filogenético y revisión taxonómica de las 12 especies previamente ubicadas en Tortopus, junto con 3 nuevas especies descriptas aquí. Sobre la base de caracteres sinapomórficos de ninfas y adultos de ...
Proteoglycans and glycosaminoglycans as regulators of cancer stem cell function and therapeutic resistance
(Wiley Blackwell Publishing, Inc, 2019-06-23)
In contrast to the bulk of the tumor, a subset of cancer cells called cancer stem cells (or tumor-initiating cells) is characterized by self-renewal, unlimited proliferative potential, expression of multidrug-resistance ...