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Novel rat model for neurocysticercosis using Taenia solium
(Elsevier, 2015)
Neurocysticercosis is caused by Taenia solium infecting the central nervous system and is the leading cause of acquired epilepsy and convulsive conditions worldwide. Research into the pathophysiology of the disease and ...
Naloxone and Baclofen Attenuate Ethanol's locomotor-activating effects in preweanling Sprague-Dawley Rats
(American Psychological Association, 2009-02)
Heterogeneous rat strains appear to be particularly sensitive to the sedative effects of ethanol as adults and insensitive to ethanol's stimulant effects. Recently, the authors found that ethanol induces stimulant effects ...
Modeling the Evans Blue Dilution Method for the Measurement of Plasma Volume in Small Animals: A New Optimized Method
(Springer, 2018)
The measurement of plasma volume (V p ) in humans and animals is frequently performed by the Evans blue dye dilution method. However, after injection of Evans blue into the circulation, no steady state is observed because ...
Lactation deficit in OFA hr/hr rats may be caused by differential sensitivity to stress compared with Wistar and Sprague Dawley rats
(Taylor & Francis Ltd, 2012-07)
OFA hr/hr (OFA) rats present a major lactation deficit that impairs offspring survival. To explore whether abnormal stress responsiveness causes this deficit, we compared their hormonal (prolactin, progesterone, and ...
Preclinical studies on the pharmacokinetics, safety, and toxicology of oxfendazole: toward first in human studies
(SAGE Publications, 2015)
A 2-week study in rats identified target organs of oxfendazole toxicity to be bone marrow, epididymis, liver, spleen, testis, and thymus. Female rats had greater oxfendazole exposure and exhibited toxicities at lower doses ...
Anti-inflammatory activity of Urera baccifera (Urticaceae) in Sprague-Dawley rats
(Universidad de Costa Rica, 1999)
Ethanol induces locomotor activating effects in preweanling Sprague-Dawley rats
(Elsevier Science Inc, 2009-02)
Abuse of drugs exerts biphasic motor activity effects, which seem to be associated with their motivational effects. In the case of ethanol, heterogenous rat strains appear to be particularly sensitive to the sedative effects ...
Anti-inflammatory activity of aqueous extracts of five Costa Rican medicinal plants in Sprague-Dawley rats
(Universidad de Costa Rica, 1999)