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Lactation deficit in OFA hr/hr rats may be caused by differential sensitivity to stress compared with Wistar and Sprague Dawley rats
(Taylor & Francis Ltd, 2012-07)
OFA hr/hr (OFA) rats present a major lactation deficit that impairs offspring survival. To explore whether abnormal stress responsiveness causes this deficit, we compared their hormonal (prolactin, progesterone, and ...
Role of prolactin in the regulation of cytosolic NADP isocitrate dehydrogenase in the liver of the male rat
(Taylor & Francis, 2003-05)
The activity of cytosolic NADP-linked isocitrate dehydrogenase (ICDH) in rat liver was determined. The administration of 2-bromo-α-ergocryptine (CB-154) to male rats produced a significant increase of the enzyme activity ...
Biomechanical performance of diaphyseal shafts and bone tissue of femurs from hypothyroid rats
(Humana Press, 2009-12)
The bone changes in hypothyroidism are characterized by a low bone turnover with a reduced osteoid apposition and bone mineralization rate, and a decreased osteoclastic resorption in cortical bone. These changes could ...
Placental and Fetal Toxicity of Albendazole Sulphoxide in Wistar Rats
(American College of Veterinary Toxicologists, 2003-06)
This work characterized the effects of albendazole sulphoxided (ABZSO) on placental and fetal parameters in Wistar rats on day 20of gestation. (ABZSO) was fed in laboratory chow at 0. 2.5. 5. 10. 20 or 30 mg/kg/d from day ...
Anterior hypothalamic β-adrenergic activity in the maintenance of hypertension in aortic coarctated rats
(Academic Press Ltd - Elsevier Science Ltd, 2004-01)
The aim of this work was to demonstrate an alteration of the anterior hypothalamic catecholaminergic system in aortic coarctated (ACo) rats by the perfusion of β-adrenergic antagonist and the microinfusion of β-adrenergic ...
Fructose rich diet-induced allostasis aggravates metabolic syndrome development in the Polycystic Ovary Syndrome Rat Phenotype
(Nature Publishing Group, 2010-12)
Hyperandrogenemia predisposes an organism toward developing impaired insulin sensitivity. The aim of our study was to evaluate endocrine and metabolic effects during early allostasis induced by a fructose-rich diet (FRD) ...
Naloxone and Baclofen Attenuate Ethanol's locomotor-activating effects in preweanling Sprague-Dawley Rats
(American Psychological Association, 2009-02)
Heterogeneous rat strains appear to be particularly sensitive to the sedative effects of ethanol as adults and insensitive to ethanol's stimulant effects. Recently, the authors found that ethanol induces stimulant effects ...
Age-related increase in resistance to acute Trypanosoma cruzi infection in rats is associated with an appropriate antibody response
(Wiley Blackwell Publishing, Inc, 2003-07)
Inoculation at weaning with Trypanosoma cruzi in inbred 'l' rats resulted in a self-resolving acute infection characterized by marked parasitaemias, whereas challenge to adult rats revealed a mild disease with extremely ...
Non-shivering thermogenesis in four species of African mole-rats differing in their sociality
(Wiley Blackwell Publishing, Inc, 2021-09)
Many mammalian species are adapted to living in burrows for most of their lives. Inhabiting such thermally stable environments may influence the variation on the species thermogenic capacity, particularly non-shivering ...
Systemic oxidative stress in old rats is associated with both osteoporosis and cognitive impairment
(Pergamon-Elsevier Science Ltd, 2021-12)
Aging is associated both with an increase in memory loss and with comorbidities such as Osteoporosis, which could be causatively linked. In the present study, a deleterious effect on bone is demonstrated for the first time ...