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Biopharmaceuticals from microorganisms: from production to purification
(2016-12-01)
The use of biopharmaceuticals dates from the 19th century and within 5–10 years, up to 50% of all drugs in development will be biopharmaceuticals. In the 1980s, the biopharmaceutical industry experienced a significant ...
Transcription factor engineering in CHO cells for recombinant protein production
(Taylor and Francis Ltd, 2019)
The continuous increase of approved biopharmaceutical products drives the development of more efficient recombinant protein expression systems. Chinese hamster ovary (CHO) cells are the mainstay for this purpose but have ...
Aqueous extraction of maize endosperm: Insights for recombinant protein hosts based on downstream processing
(Elsevier Sci LtdOxfordInglaterra, 2005)
Biogenéricos: Un Estudio de Vigilancia Tecnológica para el Caso de la Situación en Chile
(Universidad Alberto Hurtado. Facultad de Economía y Negocios, 2014)
L-asparaginase production review: bioprocess design and biochemical characteristics
(2021-06-01)
Abstract: In the past decades, the production of biopharmaceuticals has gained high interest due to its great sensitivity, specificity, and lower risk of negative effects to patients. Biopharmaceuticals are mostly therapeutic ...
Therapeutic monoclonal antibodies: scFv patents as a marker of a new class of potential biopharmaceuticals
(Universidade de São Paulo, Faculdade de Ciências Farmacêuticas, 2011)
Monoclonal antibodies represent the fastest growing class of biopharmaceutical products and have a host of applications in medical research, diagnosis, therapy, and basic science. The production of recombinant monoclonal ...
Semliki forest virus as a vector: Pros and cons for its use in biopharmaceuticals production
(2013-09-01)
The number of biopharmaceuticals for medical and veterinarian use produced in mammalian cells is increasing year after year. All of them are obtained by stable recombinant cell lines. However, it is recognized that transient ...
Semliki Forest Virus as a Vector: Pros and Cons for Its Use in Biopharmaceuticals Production
(Inst Tecnologia Parana, 2013-09-01)
The number of biopharmaceuticals for medical and veterinarian use produced in mammalian cells is increasing year after year. All of them are obtained by stable recombinant cell lines. However, it is recognized that transient ...
Aqueous extraction of recombinant human proinsulin from transgenic maize endosperm
(Amer Chemical SocWashingtonEUA, 2005)
NUCEL (Cell and Molecular Therapy Center): A multidisciplinary center for translational research in Brazil
(HUMANA PRESS INC, 2008)
Social and economical development is closely associated with technological innovation and a well-developed biotechnological industry. In the last few years, Brazil`s scientific production has been steadily increasing; ...