The objectives of this work were to establish the utility of chitosan of Chilean production, as an excipient suitable for producing a prolonged-release hydrophilic matrix, and to compare two matrix systems, one with chitosan ...

The aim of this work was to develop prolonged diltiazem hydrochloride release matrices based on alginate-gelatin mixtures and establish the drug release mechanism. The erosion, swelling, and dissolution behavior of the ...

The aim of this work was to study the performance of chitosan (CB) grafted with acrylamide (CB-g-A) as prolonged drug release matrix as compared with unmodified chitosan. A non-pH dependent swelling behaviour for the matrix ...

Abstract: A temporal relationship between the nocturnal rise in melatonin secretion and the increase in sleep propensity at the beginning of the night, coupled with the sleep-promoting effects of exogenous melatonin, ...

The aim of this work was to evaluate the possibility of using mixtures and/or polyelectrolyte complexes from both chitosan-alginate and chitosan-carrageenan as prolonged drug release systems. Different dissolution profiles ...

The aim of this work was to develop prolonged diltiazem hydrochloride release matrices based on alginate-gelatin mixtures and establish the drug release mechanism. The erosion, swelling, and dissolution behavior of the ...