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Differentially poised vesicles underlie fast and slow components of release at single synapses
(Rockefeller University Press, 2020)
In several types of central mammalian synapses, sustained presynaptic stimulation leads to a sequence of two components of synaptic vesicle release, reflecting the consecutive contributions of a fast-releasing pool (FRP) ...
Heme Iron Release from Alginate Beads at In Vitro Simulated Gastrointestinal Conditions
(Humana Press Inc., 2016)
Heme iron (Fe) release from alginate beads at in vitro simulated gastrointestinal conditions for potential use as oral heme Fe supplement was studied. Five beads at different ratios of sodium alginate (SA)-to-spray-dried ...
The heat released during catalytic turnover enhances the diffusion of an enzyme
(Macmillan, 2015)
Recent studies have shown that the diffusivity of enzymes increases
in a substrate-dependent manner during catalysis1,2. Although this
observation has been reported and characterized for several different
systems3–10, ...
Complexin: Masterpiece in Vesicle Cycling and Release
(Cell Press, 2015)
Inhibitory ryanodine prevents ryanodine receptor-mediated Ca2+ release without affecting endoplasmic reticulum Ca2+ content in primary hippocampal neurons
(Academic Press, 2015)
Ryanodine is a cell permeant plant alkaloid that binds selectively and with high affinity to ryanodine
receptor (RyR) Ca2þ release channels. Sub-micromolar ryanodine concentrations activate RyR channels
while micromolar ...
Effect of tachycardia on myocardial sarcoplasmic reticulum and Ca2+ dynamics: a mechanism for preconditioning?
(ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, 2003-12)
We have previously demonstrated that brief episodes of tachycardia prior to a prolonged occlusion of a coronary artery, followed by reperfusion, substantially reduce the infarct size. Adenosine receptors and mitochondrial ...
Shapley Supercluster Survey: construction of the photometric catalogues and i-band data release
(Oxford University Press, 2015)
The Shapley Supercluster Survey is a multi-wavelength survey covering an area of similar to 23 deg(2) (similar to 260 Mpc(2) at z = 0.048) around the supercluster core, including nine Abell and two poor clusters, having ...
Effects of adrenalectomy on the stress-induced changes in ovarian sympathetic tone in the rat
(HUMANA PRESS INC, 1999-04)
A 3-wk period of stress promotes the development of ovarian cysts in rats apparently mediated by increased sympathetic nerve activity and ovarian steroid secretion. After 11 wk of stress, these parameters are indistinguishable ...
Optimal release programs for dengue prevention using aedes aegypti mosquitoes transinfected with wmel or wmelpop wolbachia strains
(AIMS Press, 2021-03)
In this paper, we propose a dengue transmission model of SIR(S)-SI type that accounts for two sex-structured mosquito populations: the wild mosquitoes (males and females that are Wol- bachia-free), and those deliberately ...