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New perspective on the pathophysiology of panic: merging serotonin and opioids in the periaqueductal gray
(Associação Brasileira de Divulgação Científica, 2012)
Panic disorder patients are vulnerable to recurrent panic attacks. Two neurochemical hypotheses have been proposed to explain this susceptibility. The first assumes that panic patients have deficient serotonergic inhibition ...
Burden and Distress in Caregivers of Patients With Panic Disorder and Agoraphobia
(Lippincott Williams & Wilkins, 2017-01-01)
We estimated the prevalence, severity, and correlates of burden and distress in caregivers of patients with panic disorder and agoraphobia. The instruments used in this cross-sectional study with 40 caregivers and 40 ...
The hypothalamic-pituitary-adrenal axis in anxiety and panic
(Pontificia Universidade Católica do Rio de JaneiroUniversidade de BrasíliaUniversidade de São Paulo, 2010)
This review article focuses on the differential activation of the hypothalamic-pituitary-adrenal (HPA) axis in generalized anxiety and panic. The results of experimental studies that assayed adrenocorticotropic hormone, ...
Relationship between Panic Buying and Per Capita Income during COVID-19
(Mdpi, 2020-12-01)
Panic buying and hoarding express common human behavior in times of crisis. Early in COVID-19, as the pandemic crisis intensified, toilet paper was one of the emblematic cases of panic buying. Using a Geographic Information ...
Neurobiology of panic disorder: From animal models to brain neuroimaging
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
Evidence from animal models of anxiety has led to the hypothesis that serotonin enhances inhibitory avoidance (related to anxiety) in the forebrain, but inhibits one-way escape (panic) in the midbrain periaqueductal gray ...
Panic-like escape response elicited in mice by exposure to CO2, but not hypoxia
(2018-02-02)
Exposure to elevated concentrations of CO2 or hypoxia has been widely used in psychiatric research as a panic provoking stimulus. However, the use of these respiratory challenges to model panic-like responses in experimental ...
Potentiation of panic-like behaviors of the rat by subconvulsive doses of strychnine
(Elsevier B.V., 2004-01-01)
The present study was carried out to determine possible panicogenic effects of strychnine administered in subconvulsive doses to rats. Two experiments were conducted to assess two major features of panic in animal models: ...
Unpredictable chronic prenatal stress and manifestation of generalized anxiety and panic in rat's offspring
(2018-07-13)
Often the manifestation of anxiety cannot be explained by known environmental or hereditary factors. With this perspective, it has been reported that prenatal stress may lead to emotional disturbances in the offspring. ...
Depersonalization and personality in panic disorder
(W B SAUNDERS CO-ELSEVIER INC, 2011)
Background: Prevalence and clinical correlates of depersonalization symptoms have been associated with panic disorder. Personality traits might increase the likelihood of experiencing depersonalization symptoms or ...
(1)H magnetic resonance spectroscopy imaging of the hippocampus in patients with panic disorder
(ELSEVIER IRELAND LTD, 2010)
Recent theories of panic disorder propose an extensive involvement of limbic system structures, such as the hippocampus, in the pathophysiology of this condition. Despite this, no prior study has examined exclusively the ...