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Parathyroid hormone: an early predictor of symptomatic hypocalcemia after total thyroidectomy
(Sociedade Brasileira de Endocrinologia e Metabologia, 2012-04-01)
OBJECTIVE: The purpose of this study was to evaluate if the measurement of peri-operative parathyroid hormone (PTH) is able to identify patients with increased risk of developing symptoms of hypocalcemia. SUBJECTS AND ...
Intermittent PTH1-34 Causes DNA and Chromosome Breaks in Osteoblastic and Nonosteoblastic Cells
(Springer, 2010-11-01)
Toxicological studies have demonstrated that intermittent PTH1-34 treatment is associated with an increased incidence of osteosarcoma in Fischer 344 rats. Comet and micronucleus (MN) tests, standard methods to evaluate ...
Valores de paratormônio obtidos com ensaios imunométricos dependem da especificidade do anticorpo amino terminal empregado
(Sociedade Brasileira de Endocrinologia e Metabologia, 2004-08-01)
Introduction of 2nd generation immunometric assays for the measurement of serum parathyroid hormone (PTH), turned them more available, simple and rapid. These methods, based on double identification of the PTH molecule, ...
Utilidade da medida de PTH intra-operatório no tratamento cirúrgico do hiperparatiroidismo primário e secundário: análise de 109 casos
(Sociedade Brasileira de Endocrinologia e Metabologia, 2006-10-01)
INTRODUCTION: Intraoperative parathyroid hormone measurement (IO-PTH) was first described in 1988 and it's potentially useful in predicting cure after parathyroidectomy. The aim of this study was to evaluate IO-PTH decay ...
Usefulness of a rapid immunometric assay for intraoperative parathyroid hormone measurements
(Associação Brasileira de Divulgação Científica, 2003-06-01)
Intraoperative parathyroid hormone (IO-PTH) measurements have been proposed to improve operative success rates in primary, secondary and tertiary hyperparathyroidism (PHP, SHP and THP). Thirty-one patients requiring ...
Diagnóstico Laboratorial do Hiperparatiroidismo Primário
(Sociedade Brasileira de Endocrinologia e Metabologia, 2002-02-01)
Primary hyperparathyroidism (PHP) is a frequent endocrinopathy. Increased serum calcium levels may be considered as a potential marker for parathyroid autonomy and this explains why PHP should be routinely investigated in ...
Evolution of PTH assays
(Sociedade Brasileira de Endocrinologia e Metabologia, 2006-08-01)
PTH metabolism is complex and the circulating forms include the intact 1-84 molecule as well as several carboxyl-terminal fragments. The first generation of PTH assays included several types of competitive assays, with ...
Hiperparatireoidismo em gatos com hipertireoidismo experimental
(Universidade Federal de Minas Gerais (UFMG), Escola de Veterinária, 2008-06-01)
Os efeitos do hipertireoidismo experimental, 150µg/kg/dia/42 dias de levotiroxina sódica, na homeostase do cálcio foram estudados em 14 gatos sem raça definida, com idades entre um e três anos. A cada 14 dias foram colhidas ...
Expanding the spectrum of PTH1R mutations in patients with primary failure of tooth eruption
(2013-06-17)
Objectives: Primary failure of tooth eruption (PFE) is a rare autosomal-dominant disease characterized by severe lateral open bite as a consequence of incomplete eruption of posterior teeth. Heterozygous mutations in the ...
Does hypophosphataemia induce hypoparathyroidism in pre-dialysis patients?
(Oxford Univ Press, 1998-01-01)