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The role of oxidative stress in the pathophysiology of gestational diabetes mellitus
(Mary Ann Liebert Inc, 2011-10)
Normal human pregnancy is considered a state of enhanced oxidative stress. In pregnancy, it plays important roles in embryo development, implantation, placental development and function, fetal development, and labor. ...
Nitric oxide accumulation is required to protect against iron-mediated oxidative stress in frataxin-deficient Arabidopsis plants
(Elsevier Science, 2009-01)
Frataxin is a mitochondrial protein that is conserved throughout evolution. In yeast and mammals, frataxin is essential for cellular iron (Fe) homeostasis and survival during oxidative stress. In plants, frataxin deficiency ...
Phospholipase D signaling during oxidative stress
(Transworld, 2013)
Compared to other organs, the brain contains a high amount of phospholipids with a structural role in maintaining cellular membrane fluidity and properties; however, their specific function in the pathogenesis of the nervous ...
Nitric oxide and metals toxicity
(Research Singpost, 2007)
Numerous studies, focusing on the effects of environmental pollutants such as metals of industrial use, appear to affect intracellular homeostasis, particularly cadmium, arsenic mercury, nickel, chromium, manganese, copper, ...
Oxidative Stress in Muscle Diseases: Current and Future Therapy
(Landes Bioscience, 2018-04)
Oxidative stress can be considered a consequence ofimbalance in the formation of reactive oxygen species(ROS) and antioxidant defense systems, in which mitochondriaappear to be the main source of ROS production. A keyconcern ...
Time course and mechanism of brain oxidative stress and damage for redox active and inactive transition metals overload
(Instituto de Histología y Embriología, 2016-04)
The objective of this work was to study the in vivo time course of biochemical processes of oxidative damage in the brain of Sprague-Dawley rats that received an acute overload of the redox active metals iron (Fe) and ...
Oxidative stress and altered steroidogenesis in the ovary by cholinergic stimulation of coeliac ganglion in the first proestrous in rats. Implication of nitric oxide
(Academic Press Inc Elsevier Science, 2016-02-29)
An ex-vivo Coeliac Ganglion-Superior Ovarian Nerve-Ovary (CG-SON-O) system from virgin rats in the first proestrous was used to test whether cholinergic stimulation of CG affects oxidative status and steroidogenesis in the ...
Mitochondrial Alterations and Oxidative Stress in Cystic Fibrosis
(Springer, 2019)
Cystic fibrosis (CF) is the most frequent autosomal recessive disease and is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Since the discovery of the deletion in the phenylalanine ...
Serum oxidative stress parameters of women with hypothyroidism
(Sociedad de Medicina y Ciencias Naturales de Parma, 2009-08)
In order to study the effects of hypothyroidism on parameters of oxidative stress in woman, we determined the values of thiobarbituric acid reactive substances (TBARS), Nitric Oxide (NO) and Paraoxonase (PON-1) using ...