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Possible role of seasonality and harmful algal blooms (HAB) on the oxidative and nitrosative metabolisms in hemocytes
(Elsevier Science Inc., 2020-06)
Bivalves survive to biotoxin consumption but their metabolism could be affected. The objective of this work was to study the oxidative and nitrosative changes in the hemocytes of the mussel Mytilus edulis platensis in ...
Nitrosative stress and apoptosis in non-anemic healthy rats induced by intravenous iron sucrose similars versus iron sucrose originator
(Springer, 2015-04)
Iron can both induce and inhibit nitrosative stress. Intracellular iron levels play an important role in nitric oxide (NO•) signaling mechanisms. Depending on various factors, such as the cell's redox state and transition ...
Nitrosative Stress and Apoptosis by Intravenous Ferumoxytol, Iron Isomaltoside 1000, Iron Dextran, Iron Sucrose, and Ferric Carboxymaltose in a Nonclinical Model
(Thieme Medical Publ Inc, 2015-07)
Iron is involved in the formation as well as in the scavenging of reactive oxygen and nitrogen species. Thus, iron can induce as well as inhibit both oxidative and nitrosative stress. It also has a key role in reactive ...
Effect of Arsenic on Nitrosative Stress in Human Breast Cancer Cells and its Modulation by Flavonoids
(Bentham Science Publishers, 2013-10)
Arsenic (As) is used in the treatment of leukaemia and breast cancer due to its strong oxidative cytotoxic action. However, it is also cytotoxic to normal cells. One proposed anticancer mechanism induced by As might be ...
Nitrosation of N-methylhydroxylamine by nitroprusside: a kinetic and mechanistic study
(Royal Society of Chemistry, 2008-12)
The kinetics of the reaction between aqueous solutions of Na 2[Fe(CN)5NO]•2H2O (sodium pentacyanonitrosylferrate(ii), nitroprusside, SNP) and MeN(H)OH (N-methylhydroxylamine, MeHA) has been studied by means of UV-vis ...
Nitrosative stress in human spermatozoa causes cell death characterized by induction of mitochondrial permeability transition-driven necrosis
(Asian Society of Andrology, 2018-11)
Peroxynitrite is a highly reactive nitrogen species and a potent inducer of apoptosis and necrosis in somatic cells. Peroxynitrite-induced nitrosative stress has emerged as a major cause of impaired sperm function; however, ...
Naringin prevents the inhibition of intestinal Ca2+ absorption induced by a fructose rich diet
(Elsevier Science Inc, 2017-12)
This study tries to elucidate the mechanisms by which fructose rich diets (FRD) inhibit the rat intestinal Ca2+ absorption, and determine if any or all underlying alterations are prevented by naringin (NAR). Male rats were ...
Metipranolol promotes structure and function of retinal photoreceptors in the rd10 mouse model of human retinitis pigmentosa
(Wiley Blackwell Publishing, Inc, 2019-01)
Metipranolol is a b-adrenergic receptor antagonist that is given orally for the treatment of hypertension and also applied topically to the cornea for treating glaucoma. It also inhibits nitrosative stress which has ...
Endometriosis progression in tumor necrosis factor receptor p55-deficient mice: Impact on oxidative/nitrosative stress and metallomic profile
(Elsevier Gmbh, 2019-03)
The present study was conducted to investigate whether the deficiency of tumor necrosis factor receptor p55 (TNFRp55) modulates oxidative/nitrosative stress and metallomic profile into the peritoneal cavity during the ...
Combined treatment of menadione and calcitriol increases the antiproliferative effect by promoting oxidative/nitrosative stress, mitochondrial dysfunction, and autophagy in breast cancer mcf-7 cells
(National Research Council Canada-NRC Research Press, 2020-08)
The aim of this study was to determine new insights into the molecular mechanisms involved in the antiproliferative action of menadione + calcitriol (MEN+D) on MCF-7 cells. After 24 h, MEN+D inhibited the cell growth but ...