Buscar
Mostrando ítems 1-10 de 844
Monocytes from Pregnant Women with Pre-Eclampsia are Polarized to a M1 Phenotype
(Wiley-Blackwell, 2014-07-01)
Problem This study evaluated whether the monocyte inflammatory state in pre-eclampsia (PE) might be associated with polarization to either M1 classically or M2 alternatively activated monocyte subsets. Method of Study ...
Standardized Flow Cytometry Assay for Identification of Human Monocytic Heterogeneity and LRP1 Expression in Monocyte Subpopulations: Decreased Expression of This Receptor in Nonclassical Monocytes
(Wiley-liss, Div John Wiley & Sons Inc, 2014-07)
In this article, we present a flow cytometry assay by which human blood monocyte sub-populations—classical (CD1411CD162), intermediate (CD1411CD161), and non-classical (CD141CD1611) monocytes—can be determined. Monocytic ...
Prostaglandin E-2 inhibits Paracoccidioides brasiliensis killing by human monocytes
(Elsevier B.V., 2007-05-01)
Human monocytes lacked fungicidal activity against high virulence strain of Paracoccidioides brasiliensis, even after IFN-gamma activation. However, monocytes treated with indomethacin exhibited an effective killing against ...
Monocyte phenotypes: when local education counts
(Rockefeller Univ Press, 2015-04)
Monocytes are a heterogeneous population of phagocytic cells that are generated in the bone marrow and released into the bloodstream. There are two main monocyte subsets in mice: “inflammatory” monocytes that are Ly6Chi ...
Interleukin-6 treatment enhances human monocyte permissiveness for Paracoccidioides brasiliensis growth by modulating cytokine production
(Taylor & Francis Ltd, 2009-01-01)
The effect of interleukin (IL)-6 on cytokine production was evaluated in human monocyte cultures infected with the virulent strain of Paracoccidioides brasiliensis (Pb18). Peripheral blood monocytes from healthy individuals ...
Production of pro- and anti-inflammatory cytokines by monocytes from patients with paracoccidioidomycosis
(Elsevier B.V., 2003-04-01)
Monocytes and macrophages can produce a large repertoire of cytokines and participate in the pathogenesis of granulomatous diseases. We investigated the production of pro- and anti-inflammatory cytokines by monocytes from ...
Interleukin-15 augments oxidative metabolism and fungicidal activity of human monocytes against Paracoccidioides brasiliensis
(Instituto Oswaldo Cruz, Ministério da Saúde, 2010-11-01)
Interleukin (IL)-15 is a pleiotropic cytokine that regulates the proliferation and survival of many cell types. IL-15 is produced by monocytes and macrophages against infectious agents and plays a pivotal role in innate ...
Progesterone and vitamin D downregulate the activation of the NLRP1/NLRP3 inflammasomes and TLR4-MyD88-NF-κB pathway in monocytes from pregnant women with preeclampsia
(2021-04-01)
This study evaluated the in vitro modulatory effect of progesterone (PG) and vitamin D (VD) on NLRP1/NLRP3 inflammasomes and TLR4/NF-κB pathway in monocytes from pregnant women with preeclampsia (PE). Monocytes from 20 ...
TNF-alpha activates human monocytes for Paracoccidioides brasiliensis killing by an H2O2-dependent mechanism
(Taylor & Francis Ltd, 2006-06-01)
Human monocytes activated by recombinant tumor necrosis factor alpha (TNF-alpha) exhibited significant fungicidal activity on the yeast cells of a highly virulent strain of Paracoccidioides brasiliensis. This process was ...