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The Light Chain 1 Subunit of the Microtubule-Associated Protein 1B (MAP1B) Is Responsible for Tiam1 Binding and Rac1 Activation in Neuronal Cells
(2012)
Microtubule-associated protein 1B (MAP1B) is a neuronal protein involved in the stabilization of microtubules both in the axon and somatodendritic compartments. Acute, genetic inactivation of MAP1B leads to delayed axonal ...
Colchicine attenuates left ventricular hypertrophy but preserves cardiac function of aortic-constricted rats
(Amer Physiological SocBethesdaEUA, 2003)
Cytoskeletal-inhibiting drugs and low levels of Ca2+induce subcellular alterations in Lamiaceae glandular trichomes
(2021-07-01)
Subcellular features of glandular trichomes have been extensively studied in plants of a variety of families, but the role that the cytoskeleton plays in gland morphology and functioning has been neglected. We investigated ...
A novel method for purification of polymerizable tubulin with a high content of the acetylated isotype
(Portland Press, 2013-02)
Tubulin can be acetylated/deacetylated on Lys40 of the α-subunit. Studies of the post-translational acetylation/deacetylation of tubulin using biochemical techniques require tubulin preparations that are enriched in AcTubulin ...
The MAP1B case: An old MAP that is new again
(John Wiley and Sons Inc., 2014)
© 2014 Wiley Periodicals, Inc. The functions of microtubule-associated protein 1B (MAP1B) have historically been linked to the development of the nervous system, based on its very early expression in neurons and glial ...
The role of cytoskeleton, components of inositol phospholipid signaling pathway and iron in Ehrlichia canis in vitro proliferation
(SPRINGERDORDRECHT, 2012)
Ehrlichia canis, etiologic agent of Canine Monocytic Ehrlichiosis, is an obligatory intracellular bacterium that parasitizes monocytes and macrophages. In this study we analyzed the role of the cytoskeleton specifically ...
A τ Fragment Containing a Repetitive Sequence Induces Bundling of Actin Filaments
(1993)
Abstract: Much indirect evidence suggests that the interconnections of actin microfilaments with the microtubule system are mediated by microtubule‐associated proteins (MAPs). In this study we provide new data to support ...
Oocyte meiotic-stage-specific differences in spindle depolymerization in response to temperature changes monitored with polarized field microscopy and immunocytochemistry
(ELSEVIER SCIENCE INCNEW YORK, 2013-08-02)
Objective: To compare the polymerization status of mouse oocyte spindles exposed to various temperatures at various stages of meiosis. Design: Experimental animal study. Setting: University animal laboratory. Animal(s): ...
Calcium and gadolinium ions stimulate the GTPase activity of purified chicken brain tubulin through a conformational change
(1996)
Ca2+ and Gd3+ stimulated the GTPase activity of chicken brain tubulin 13- and 26-fold, respectively. Mg2+, Tb3+, and Na+ had no effect. This GTPase activity showed a saturation behavior with Ca2+ and Gd3+ with a maximal ...
Reversed-phase high-performance liquid chromatography: A fast and efficient analytical method to quantify docetaxel-loaded pegylated liposomes in release study
(2021-01-01)
Docetaxel is an anticancer that belongs to the family of taxanes and acts in the inhibition of cell proliferation through the polymerization of microtubules. The aim of this study was the development and validation of a ...