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Role of proteases in dysfunctional placental vascular remodelling in preeclampsia
(2020-02-01)
Preeclampsia is a syndrome characterised by vascular dysfunction, impaired angiogenesis, and hypertension during pregnancy. Even when the precise pathophysiology of preeclampsia remains elusive, impaired vascular remodelling ...
Identification, recombinant production and partial biochemical characterization of an extracellular cold-active serine-metalloprotease from an Antarctic Pseudomonas isolate
(AIMS Press, 2017)
Cold-adapted enzymes are generally derived from psychrophilic microorganisms and have features that make them very attractive for industrial and biotechnological purposes. In this work, we identified a 50 kDa extracellular ...
Tubulointerstitial injury and proximal tubule albumin transport in early diabetic nephropathy induced by type 1 diabetes mellitus
(Sociedad Latinoamericana de Microscopía Electrónica y Centro Regional de Investigaciones Científicas y Tecnológicas, 2017)
A decrease in the tubular expression of albumin endocytic transporters megalin and cubilin has been
associated with diabetic nephropathy, but there are no comprehensive studies to date relating early tubulointerstitial
injury ...
Apoptosis induced by a snake venom metalloproteinase from bothrops alternatus venom in C2C12 muscle cells
(Springer, 2017)
In this study, the apoptosis inducing effects of baltergin as well as its influence on cell adhesion and migration on muscles cells in vitro were studied. Morphological analysis made by scanning electron and pase contrast ...
Infection of human monocyte-derived dendritic cells by ANDES Hantavirus enhances pro-inflammatory state, the secretion of active MMP-9 and indirectly enhances endothelial permeability
(2011)
Abstract
Background
Andes virus (ANDV), a rodent-borne Hantavirus, is the major etiological agent of Hantavirus cardiopulmonary syndrome (HCPS) in South America, which is ...